catalog number :
MBS695709
products type :
Recombinant Protein
products full name :
Animal Free Animal Free Murine VEGF
products short name :
[VEGF]
products name syn :
[Vascular Endothelial Growth factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF 165 ]
other names :
[VEGF, partial; Vascular endothelial growth factor A; vascular endothelial growth factor A; VPF; VEGF-A; vascular permeability factor; Vascular permeability factor; VPF]
other gene names :
[VEGFA; VEGFA; VEGF; VEGF; VEGF-A; VPF]
uniprot entry name :
VEGFA_PIG
reactivity :
Animal Free Animal Free Murine VEGF
sequence :
MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYPDEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQIMRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC
SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRCDKPRR
purity :
>=98% by SDS-PAGE gel and HPLC analyses.
form :
Sterile filtered through a 0.2 micron filter. Lyophilized from 20 mM Acetic Acid.
storage stability :
Store at -20°C
other info1 :
Authenticity: Verified by N-terminal and Mass Spectometry analyses (when applicable). Endotoxin: Endotoxin level is <0.1 ng/ug of protein (<1EU/ug). Protein Content: Verified by UV Spectroscopy and/or SDS-PAGE gel. Biological activity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-5.0 ng/mL.
other info2 :
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage,It is recommended to further dilute in a buffer containing a carrier protein ( example 5% Trehalose) and store in working aliquots at -20°C to -80°C .
ncbi acc num :
AIE11421.1
ncbi pathways :
Axon Guidance Pathway (1014044); Bladder Cancer Pathway (84522); Bladder Cancer Pathway (527); Cellular Response To Hypoxia Pathway (1013761); Cellular Responses To Stress Pathway (1013760); Cytokine-cytokine Receptor Interaction Pathway (84463); Cytokine-cytokine Receptor Interaction Pathway (460); Developmental Biology Pathway (1014043); EPH-Ephrin Signaling Pathway (1014071); EPHA-mediated Growth Cone Collapse Pathway (1014072)
uniprot summary :
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin ().