protein

Mouse RELM alpha

MBS691667

0.005 mg

200 USD

Recombinant Protein

Mouse RELM alpha

[RELM alpha]

[Retnla; HIMF; Xcp2; Fizz1; RELMa; Fizz-1; RELMalpha; RELM-alpha; 1810019L16Rik]

[resistin-like alpha; Resistin-like alpha; resistin-like alpha; found in inflammatory zone 1; hypoxia-induced mitogenic factor; cysteine-rich secreted protein FIZZ1; cysteine-rich secreted protein A12-gamma; parasite-induced macrophage novel gene 1 protein; resistin like alpha; Cysteine-rich secreted protein A12-gamma; Cysteine-rich secreted protein FIZZ1; Hypoxia-induced mitogenic factor; Parasite-induced macrophage novel gene 1 protein; RELMalpha]

[RELM alpha]

[Retnla; Retnla; HIMF; Xcp2; Fizz1; RELMa; Fizz-1; RELMalpha; RELM-alpha; 1810019L16Rik; Fizz1; Himf; Pmng1]

RETNA_MOUSE

E Coli

Mouse

89

MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCP AGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS

> 98% by SDS-PAGE & HPLC analyses

Lyophilized

The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles.

Endotoxin Level: < 0.1 ng per ug of RELM-alpha. Structural Information: Monomeric. Endotoxin level: <0.1 ng/ug of protein (<1EU/ug). Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Biological Activity: Data not available.

Cytokines & Growth Factors

RELMalpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELMalpha and RELMbeta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMalpha and Resistin are secreted exclusively by adipocytes while RELMbeta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELMalpha re still unknown. Recombinant murine RELMalpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.

103472022

NP_065255.2

NM_020509.3

Q9EP95

10 kDa

Function: Probable hormone. Plays a role in pulmonary vascular remodeling. Ref.7. Subunit structure: Monomer. Ref.6. Subcellular location: Secreted. Tissue specificity: Highest levels in adipose tissue. Sequence similarities: Belongs to the resistin/FIZZ family. Sequence caution: The sequence BAB25104.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

0.005 mg

200 USD

0.025 mg

340