product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti-Human IL-19
catalog :
MBS690907
quantity :
0.1 mg
price :
475 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
(1G54)
reactivity :
human
application :
western blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS690907
products type :
Antibody
products full name :
Mouse Anti-Human IL-19
products short name :
IL-19
products name syn :
IL19; MDA1; NG.1; ZMDA1; IL-10C
other names :
interleukin-19 isoform 2; Interleukin-19; interleukin-19; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; interleukin 19; Melanoma differentiation-associated protein-like protein; NG.1
products gene name :
IL-19
other gene names :
IL19; IL19; MDA1; NG.1; ZMDA1; IL-10C; ZMDA1; IL-19
uniprot entry name :
IL19_HUMAN
clonality :
Monoclonal
isotype :
IgG2
clone :
(1G54)
host :
Mouse
reactivity :
Human
sequence length :
177
purity :
Protein G chromatography
form :
Lyophilized
storage stability :
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
tested application :
Western Blot (WB), Neutr
app notes :
Western Blot (WB): 1:500-1:2000. Neutralization of IL-19 bioactivity: Yes
other info1 :
Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-19. Protein RefSeq: NP_715639.1. mRNA RefSeq: NM_153758
other info2 :
Antigen: recombinant human IL-19. Reconstitution: Reconstitute the antibody with 200ul sterile PBS and the final concentration is 500ug/ml. Remarks: This antibody was selected for its ability to detect human IL-19.
products description :
Human Interleukin 19 (IL-19) is a member of the IL-10 family of related cytokines. IL-19 contains seven helices and is secreted as a 35 kDa glycosylated monomer. IL-19 expression has been observed in keratinocytes and monocytes. IL-19 binds a receptor complex consisting of IL-20R alpha and the IL-20 R beta. This receptor complex is also shared by IL-20 and IL-24.
ncbi gi num :
30795208
ncbi acc num :
NP_037503.2
ncbi gb acc num :
NM_013371.3
uniprot acc num :
Q9UHD0
ncbi mol weight :
20,452 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL23-mediated Signaling Events Pathway (138000); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488)
ncbi summary :
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis . By similarity. Subcellular location: Secreted. Sequence similarities: Belongs to the IL-10 family.
size1 :
0.1 mg
price1 :
475 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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