product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Hamster Anti-Mouse CD28
catalog :
MBS690499
quantity :
0.1 mg
price :
490 USD
clonality :
monoclonal
host :
golden hamster
conjugate :
nonconjugated
clone name :
[(MAB0711)]
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, FACS
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS690499 image 1
Formalin fixed and paraffin embedded mouse thymus tissue section was subjected to IHC staining of CD28 using MBS690499 (Left panel: Red Pulp, Right panel: White Pulp)
image 2 :
MyBioSource MBS690499 image 2
Formalin fixed and paraffin embedded mouse tumor section was subjected to IHC staining of CD28 using MBS690499 (Left panel: x20; Right panel: x40).
product information
catalog number :
MBS690499
products type :
Antibody
products full name :
Hamster Anti-Mouse CD28
products short name :
[CD28]
products name syn :
[Anti mouse CD28]
other names :
[T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; CD28 antigen]
products gene name :
[CD28]
other gene names :
[Cd28; Cd28]
uniprot entry name :
CD28_MOUSE
clonality :
Monoclonal
isotype :
IgG
clone :
[(MAB0711)]
host :
Syrian Hamster
reactivity :
Mouse
sequence length :
218
specificity :
This antibody was selected for its ability to detect mouse CD28
purity :
Protein A/G affinity chromatography
form :
Lyophilized
storage stability :
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least for six months without detectable loss of activity. Shipping: 4°C or RT
tested application :
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
app notes :
Immunohistochemistry (Paraffin): 1:50-300 . Flow Cytometery: 1:100-1000
image1 heading :
Immunohistochemistry
image2 heading :
Immunohistochemistry
other info1 :
Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a Golden Syrian Hamster immunized with recombinant mouse CD28 protein). IgG fraction of the culture supernatant was purified by Protein G affinity chromatography. Antigen: Recombinant mouse CD28
other info2 :
Reconstitution: Reconstitute the antibody with 400 ul sterile PBS and the final concentration is 500 ug/ml. Reconstitution Buffer: PBS (sterile)
products description :
CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Mouse CD28 is expressed constitutively on virtually 100% of mouse Tcells and on developing thymocytes.
ncbi gi num :
161484597
ncbi acc num :
NP_031668.3
ncbi gb acc num :
NM_007642.4
uniprot acc num :
P31041
ncbi mol weight :
25,243 Da
ncbi pathways :
Allograft Rejection Pathway (83316); Allograft Rejection Pathway (535); Autoimmune Thyroid Disease Pathway (83314); Autoimmune Thyroid Disease Pathway (533); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); Graft-versus-host Disease Pathway (83317); Graft-versus-host Disease Pathway (536); Inflammatory Response Pathway (198280); Intestinal Immune Network For IgA Production Pathway (128761)
uniprot summary :
Function: Possibly involved in T-cell activation. Subunit structure: Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70 . By similarity. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.
size1 :
0.1 mg
price1 :
490 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!