product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti-Human IL-17B receptor
catalog :
MBS690413
quantity :
0.1 mg
price :
490 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[(9J28)]
reactivity :
human
application :
western blot
more info or order :
product information
catalog number :
MBS690413
products type :
Antibody
products full name :
Mouse Anti-Human IL-17B receptor
products short name :
[IL-17B receptor]
products name syn :
[IL17RB; CRL4; EVI27; IL17BR; IL17RH1]
other names :
[interleukin-17 receptor B; Interleukin-17 receptor B; interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1; interleukin 17 receptor B; Cytokine receptor-like 4; IL-17 receptor homolog 1; IL-17Rh1; IL17Rh1; Interleukin-17B receptor]
products gene name :
[IL-17B receptor]
other gene names :
[IL17RB; IL17RB; CRL4; EVI27; IL17BR; IL17RH1; CRL4; EVI27; IL17BR; IL-17 receptor B; IL-17RB; IL-17Rh1; IL17Rh1]
uniprot entry name :
I17RB_HUMAN
clonality :
Monoclonal
isotype :
IgG2
clone :
[(9J28)]
host :
Mouse
reactivity :
Human
sequence length :
502
purity :
Protein G chromatography
form :
Lyophilized
storage stability :
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least for six months without detectable loss of activity. Ships in blue ice.
tested application :
WB, N
app notes :
Western Blot: 1:500-1:1000. Neutralization of IL-17B-receptor bioactivity: Yes
other info1 :
Antigen : Human Recombinant IL-17B R EC domain. Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-17B R extracellular domain. Reconsitution buffer: PBS (sterile)
other info2 :
Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. Remarks: This antibody was selected for its ability to detect human IL-18B R
products description :
IL-17B receptor (IL-17B R), also known as IL-17Rh1, IL-17ER and EVI27, is a 502 amino acid (aa) type I membrane protein with a 17 aa signal peptide, a 275 aa extracellular domain, a 21 aa transmembrane domain and a 189 aa cytoplasmic tail. By alternative splicing, a secreted variant of IL-17B R has also been identified.
ncbi gi num :
27477074
ncbi acc num :
NP_061195.2
ncbi gb acc num :
NM_018725.3
uniprot acc num :
Q9NRM6
ncbi mol weight :
55,885 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL17 Signaling Pathway (920968)
ncbi summary :
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. Ref.8. Subunit structure: Interacts with DAZAP2. Ref.10. Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Tissue specificity: Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. Sequence similarities: Contains 1 SEFIR domain.
size1 :
0.1 mg
price1 :
490 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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