catalog number :
MBS690390
products full name :
Rat Anti-Mouse Tryptase-beta 1
products short name :
[Tryptase-beta 1]
products name syn :
[Tpsb2; Mcp6; Mcp-6; Mcpt6; MMCP-6; AV011504]
other names :
[tryptase; Tryptase; tryptase; mast cell protease 7; tryptase alpha/beta-1; mast cell-restricted serine protease 7; tryptase alpha/beta 1; Mast cell protease 7; mMCP-7; Tryptase alpha/beta-1]
other gene names :
[Tpsab1; Tpsab1; Mcp7; Mcp-7; Mcpt7; MMCP-7; Mcpt7; mMCP-7]
uniprot entry name :
TRYB1_MOUSE
purity :
Protein A/G chromatography
storage stability :
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity. Shipping: Blue Ice
tested application :
Western Blot (WB)
app notes :
WB: 1:250-1000
other info1 :
Antigen: Mouse recombinant protien Tryptase-beta.
other info2 :
Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
products description :
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase beta-1, also known as mast cell protease 7 (MCPT7), exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. Tryptase epsilon, also known as brain-specific serine protease 4 (BSSP-4) and brain serine protease 2 (BSP-2), is encoded by the PRSS22 gene and preferentially expressed in epithelium-rich tissues such as lung and eye. Tryptase gamma-1, also called transmembrane tryptase, is encoded by TPSG1, one of many serine protease genes clustered on human chromosome 16p13.3.
ncbi acc num :
NP_112464.4
ncbi gb acc num :
NM_031187.4
ncbi mol weight :
30,337 Da
uniprot summary :
Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Catalytic activity: Preferential cleavage: Arg- -Xaa, Lys- -Xaa, but with more restricted specificity than trypsin. Developmental stage: Is not expressed in mature serosal or mucosal mast cells and is expressed only transiently at an early stage of in vitro mast cell differentiation. Sequence similarities: Belongs to the peptidase S1 family. Tryptase subfamily.Contains 1 peptidase S1 domain.