catalog number :
MBS686075
products full name :
Goat anti-Alpha Fetoprotein, Ig Fraction- F(ab)'2 Fragment
products short name :
[Alpha Fetoprotein, Ig Fraction- F(ab)'2 Fragment]
other names :
[alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin]
other gene names :
[AFP; AFP; AFPD; FETA; HPAFP; HPAFP]
reactivity :
Alpha Fetoprotein
specificity :
Human Alphafetoprotein (AFP)
purity :
>75% based on HPLC. Proprietary 2-step fractionation procedure.
form :
Clear, colorless liquid, 0.2 um filtered
storage stability :
Store at 2-8 degree C
tested application :
Western Blot (WB), ELISA (EIA)
other info1 :
Conjugate: UnConjugated. Immunogen: Purified Human Alpha Fetoprotein (AFP). Buffer: 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
other info2 :
Preservative: 0.05% (w/v) Sodium Azide. Country of Origin: Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian.
products categories :
Primary Antibodies
ncbi acc num :
NP_001125.1
ncbi gb acc num :
NM_001134.2
ncbi mol weight :
68,678 Da
ncbi pathways :
Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
uniprot summary :
AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: cytoplasm. Molecular Function: protein binding. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of