catalog number :
MBS686012
products full name :
Goat anti-Alpha hCG, TSH, LH, FSH - Affinity Pure
products short name :
[Alpha hCG, TSH, LH, FSH]
other names :
[glycoprotein alpha subunit; Glycoprotein hormones alpha chain; glycoprotein hormones alpha chain; glycoprotein hormones, alpha polypeptide; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain]
other gene names :
[CGA; CGA; HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA; CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha]
reactivity :
Alpha hCG, TSH, LH, FSH
specificity :
Human hCG, TSH, LH, FSH, aplha-subunit
purity :
>= 95% based on SDS-PAGE. Affinity purified using solid phase Human hCG
form :
Clear, colorless liquid, 0.2 um filtered
concentration :
7.31 mg/ml (E 1% at 280 nm = 13.0)
storage stability :
Store at 2-8 degree C
app notes :
This antibody is suitable for most immunoassay formats for the detection of alpha subunit of Human hCG, TSH, LH, FSH. The optimal working dilutions should be determined by the investigator.
image1 heading :
SDS-PAGE
other info1 :
Immunogen: TSH from human pituitary glands. Buffer: 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2. Preservative: 0.05% (w/v) Sodium Azide. Country of Origin: Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian. Testing Results: Appearance: Clear,Colorless liquid. Purity: Two predominant bands at 50 and 24kDa based on SDS-PAGE.
products categories :
Primary Antibodies
ncbi mol weight :
13,075 Da
ncbi pathways :
Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Biosynthesis Of Amine And Peptide Hormones Pathway (366244); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Glucocorticoid Receptor Regulatory Network Pathway (138014); Glycoprotein Hormones Pathway (160989); GnRH Signaling Pathway (83091)
ncbi summary :
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
uniprot summary :
CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q14.3. Cellular Component: extracellular region; Golgi lumen. Molecular Function: hormone activity; protein binding. Biological Process: cell-cell signaling; peptide hormone processing; signal transduction