product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti - EBV/LMP-1
catalog :
MBS684063
quantity :
1 ml (Prediluted)
price :
175 USD
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
S20-D
reactivity :
Epstein-Barr virus
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS684063
products type :
Antibody
products full name :
Anti - EBV/LMP-1
products short name :
EBV/LMP-1
other names :
Latent membrane protein 1; Latent membrane protein 1; LMP1; hypothetical protein; Protein p63
products gene name :
EBV/LMP-1
other gene names :
LMP1; LMP1; LMP-1
uniprot entry name :
LMP1_EBVB9
clonality :
Monoclonal
clone :
S20-D
host :
Rabbit
reactivity :
Human
sequence length :
386
specificity :
Human
concentration :
1.0 mg/ml
storage stability :
Store at +4 degree C.
tested application :
Immunohistochemistry (IHC) - Formalin/Paraffin
app notes :
IHC-P dilution 1:100 - 1:200; IHC-Fr application and dilution to be tested by the user
other info1 :
Immunogen: Peptide derived from the C-terminal of Epstein-Barr virus, Latent Membrane Protein-1. Storage Buffer: 20 mM Tris-HCI, pH 8.0. Stabilizer: 20 mg/ml BSA
other info2 :
Preservative: 0.05% NaN3. Regulatory Status: ISO 9001:2008, ISO 13485:2003, CE. Immunogen: Peptide derived from the C-terminal region of Epstein-Barr virus (EBV), Latent Membrane Protein-1 (LMP-1). Antibody recognizes the epitope between Ser369 - Tyr384. Cellular localization: nucleus. Positive control: lymph node Hodgkin’s lymphoma tissue
ncbi gi num :
126373
ncbi acc num :
P03230.1
uniprot acc num :
P03230
ncbi mol weight :
41,982 Da
uniprot summary :
Function: Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the nuclear factor-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. It is a short-lived protein probably degraded by the proteasome. Subunit structure: Interacts (via PXQXT motif) with host tumor necrosis factor receptor-associated factor (TRAF) proteins TRAF1, TRAF2, TRAF3 and TRAF5. Subcellular location: Host cell membrane; Multi-pass membrane protein Ref.8. Domain: Two regions, C-terminal-activating region 1 (CTAR1) and CTAR2, have been identified within the cytoplasmic carboxy terminal domain that activates NF-kappa-B. Ref.7. Post-translational modification: Ubiquitinated on the N-terminus. Ref.8. Sequence similarities: Belongs to the herpesviridae LMP-1 family.
size1 :
1 ml (Prediluted)
price1 :
175 USD
size2 :
0.04 mL
price2 :
185
size3 :
0.1 mL
price3 :
370
size4 :
7 ml (Prediluted)
price4 :
400
size5 :
0.2 mL
price5 :
505
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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