product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti - PLAP (Placental Alkaline Phosphatase)
catalog :
MBS684024
quantity :
7 ml
price :
285 USD
clonality :
monoclonal
host :
rabbit
conjugate :
AP
clone name :
P16-D
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS684024
products type :
Antibody
products full name :
Anti - PLAP (Placental Alkaline Phosphatase)
products short name :
PLAP (Placental Alkaline Phosphatase)
other names :
Alkaline phosphatase, placental type; Alkaline phosphatase, placental type; alkaline phosphatase, placental type; Regan isozyme; glycerophosphatase; alkaline phosphomonoesterase; placental alkaline phosphatase 1; alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1
products gene name :
PLAP
other gene names :
ALPP; ALPP; ALP; PALP; PLAP; PLAP-1; PLAP; PLAP-1
uniprot entry name :
PPB1_HUMAN
clonality :
Monoclonal
clone :
P16-D
host :
Rabbit
reactivity :
Human
sequence length :
535
specificity :
Human
storage stability :
Store at +4 degree C.
tested application :
Immunohistochemistry (IHC) - Formalin/Paraffin
app notes :
IHC-P dilution 1:100 - 1:200; IHC-Fr application and dilution to be tested by the user
other info1 :
Immunogen: Peptide derived from the middle portion of human PLAP sequence. Storage Buffer: 20 mM Tris-HCI, pH 8.0. Stabilizer: 20 mg/ml BSA
other info2 :
Preservative: 0.05% NaN3. Regulatory Status: ISO 9001:2008, ISO 13485:2003, CE
ncbi gi num :
130737
ncbi acc num :
P05187.2
uniprot acc num :
P05187
ncbi mol weight :
57,954 Da
ncbi summary :
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq, Jul 2008]
uniprot summary :
Catalytic activity: A phosphate monoester + H2O = an alcohol + phosphate. Cofactor: Binds 1 magnesium ion . By similarity.Binds 2 zinc ions . By similarity. Subunit structure: Homodimer. Subcellular location: Cell membrane; Lipid-anchor GPI-anchor Ref.10 Ref.11. Polymorphism: Placental ALP is highly polymorphic, there are at least three common alleles. Miscellaneous: In most mammals there are four different isozymes: placental, placental-like, intestinal and tissue non-specific (liver/bone/kidney). Sequence similarities: Belongs to the alkaline phosphatase family. Sequence caution: The sequence AAA51708.1 differs from that shown. Reason: Erroneous initiation.
size :
7 ml
price :
285 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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