product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Anti - Cytokeratin 7
catalog :
MBS684013
quantity :
7 ml
price :
315 USD
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
R17-S
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS684013
products type :
Antibody
products full name :
Anti - Cytokeratin 7
products short name :
Cytokeratin 7
other names :
Keratin, type II cytoskeletal 7; Keratin, type II cytoskeletal 7; keratin, type II cytoskeletal 7; CK-7; keratin-7; sarcolectin; cytokeratin 7; cytokeratin-7; type-II keratin Kb7; type II mesothelial keratin K7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; keratin 7; Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7
other gene names :
KRT7; KRT7; K7; CK7; SCL; K2C7; SCL; CK-7; K7
uniprot entry name :
K2C7_HUMAN
clonality :
Monoclonal
clone :
R17-S
host :
Rabbit
reactivity :
Human
sequence length :
469
specificity :
Human
storage stability :
Store at +4 degree C.
tested application :
Immunohistochemistry (IHC) - Formalin/Paraffin
app notes :
IHC-P dilution 1:100 - 1:200; IHC-Fr application and dilution to be tested by the user
other info1 :
Immunogen: Peptide derived from C-terminal sequence of human cytokeratin 7. Storage Buffer: 20 mM Tris-HCI, pH 8.0. Stabilizer: 20 mg/ml BSA
other info2 :
Preservative: 0.05% NaN3. Regulatory Status: ISO 9001:2008, ISO 13485:2003, CE
ncbi gi num :
317373583
ncbi acc num :
P08729.5
uniprot acc num :
P08729
ncbi mol weight :
51,386 Da
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Ref.3 Ref.9. Subunit structure: Heterotetramer of two type I and two type II keratins. Interacts with eukaryotic translation initiator factor 3 (eIF3) subunit EIF3S10 and with HPV16 E7. Interacts with GPER1. Ref.8 Ref.9 Ref.15. Subcellular location: Cytoplasm Ref.2. Tissue specificity: Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus. Ref.1 Ref.4. Induction: Up-regulated by retinoic acid. Ref.2. Post-translational modification: Arg-20 is dimethylated, probably to asymmetric dimethylarginine. Ref.7. Miscellaneous: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa). Sequence similarities: Belongs to the intermediate filament family. Mass spectrometry: Molecular mass is 51203.48 Da from positions 2 - 469. Determined by MALDI. Ref.10. Sequence caution: The sequence CAA26956.2 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.
size :
7 ml
price :
315 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!