product summary
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company name :
MyBioSource
product type :
antibody
product name :
mAb to HE4
catalog :
MBS680074
quantity :
0.1 mg
price :
475 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4C9C6C11
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS680074
products type :
Antibody
products full name :
mAb to HE4
products short name :
HE4
products name syn :
mAb to HE4 (WFDC2); HE4 Monoclonal Antibody; WAP four-disulfide core domain protein 2; Epididymal secretory protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5; WFDC2; HE4; WAP5
other names :
WAP four-disulfide core domain protein 2; WAP four-disulfide core domain protein 2; WAP four-disulfide core domain protein 2; epididymal protein 4; epididymal secretory protein E4; putative protease inhibitor WAP5; WAP domain containing protein HE4-V4; major epididymis-specific protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core; WAP four-disulfide core domain 2; Epididymal secretory protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5
products gene name :
HE4
other gene names :
WFDC2; WFDC2; HE4; WAP5; EDDM4; dJ461P17.6; HE4; WAP5
uniprot entry name :
WFDC2_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
4C9C6C11
host :
Mouse
reactivity :
Human
sequence length :
124
specificity :
HE4 (Human)
form :
Affinity Purified
concentration :
1 mg/ml in PBS pH 7.2
storage stability :
Store at -20 degree C lyophilized, 4 degree C Reconstituted or sub-aliquot and -20 degree C.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
ELISA (EIA): Yes
other info1 :
Immunogen: Recombinant Protein
other info2 :
Reconstitution: Add 100ul of ddH2O to the tube containing antibody and mix to dissolve. Product Note: This antibody was raised against a recombinant protein encoding 31 a.a. - 125 a.a. of HE4. Applications reference testing against recombinant protein by MyBioSource. Independent research groups have found this antibody works in their applications. *Cross reactivity and Applications data is per published literature and/or unpublished data.
products description :
mAb to cancer antigen HE4. Human epididymis protein 4 (HE4) also designated WFDC2 is a 25 kDa biomarker for epithelial ovarian carcinomas (EOC). Human epididymis protein 4 (HE4) also designated WFDC2 is an important marker for epithelial ovarian carcinomas (EOC). HE4 has an apparent MW of 25 kDa. Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.
ncbi gi num :
56699495
ncbi acc num :
NP_006094
ncbi gb acc num :
NM_006103.3
uniprot acc num :
Q14508
ncbi mol weight :
12,993 Da
ncbi summary :
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
uniprot summary :
Subcellular location: Secreted Ref.8. Tissue specificity: Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. Ref.8. Sequence similarities: Contains 2 WAP domains.
size1 :
0.1 mg
price1 :
475 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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