This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
mAb to CA125
catalog :
MBS680034
quantity :
0.1 mg
price :
380 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
618F
reactivity :
Escherichia coli str. K-12 substr. MG1655
application :
western blot, ELISA, flow cytometry, enzyme immunoassay
product information
catalog number :
MBS680034
products type :
Antibody
products full name :
mAb to CA125
products short name :
CA125
products name syn :
MAb to CA 125; CA125 Monoclonal Antibody; Mucin-16; MUC-16; MUC16; Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125; CA125
other names :
RNA polymerase, beta prime subunit; DNA-directed RNA polymerase subunit beta'; RNA polymerase, beta prime subunit; RNA polymerase subunit beta'; Transcriptase subunit beta'
products gene name :
CA125
other gene names :
rpoC; rpoC; ECK3979; JW3951; tabB; tabB; RNAP subunit beta'
uniprot entry name :
RPOC_ECOLI
clonality :
Monoclonal
isotype :
IgG1
clone :
618F
host :
Mouse
reactivity :
Human
sequence length :
1407
specificity :
CA125 (Human)
form :
Affinity Purified
concentration :
1 mg/ml in PBS pH 7.2
storage stability :
Store at -20 degree C lyophilized, 4 degree C Reconstituted or sub-aliquot and -20 degree C.
tested application :
Western Blot (WB), ELISA (EIA), Flow Cytometry
app notes :
Western Blot: Yes - dilute at 1:1000
other info1 :
Immunogen: Endogenous Protein. Reported Reactivity: Mouse
other info2 :
Reconstitution: Add 100ul of ddH2O to the tube containing antibody and mix to dissolve. Product Note: *Cross reactivity and Applications data is per published literature and/or unpublished data
products description :
mAb to CA125. CA125 is an Ovarian Cancer Marker. CA 125 is a 250 + kDa protein. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. CA125 binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.
ncbi gi num :
16131818
ncbi acc num :
NP_418415
ncbi gb acc num :
NC_000913.2
uniprot acc num :
P0A8T7
ncbi mol weight :
155,160 Da
ncbi pathways :
Metabolic Pathways (131985); Purine Metabolism Pathway (1022); Purine Metabolism Pathway (307); Pyrimidine Metabolism Pathway (1023); Pyrimidine Metabolism Pathway (309); RNA Polymerase Pathway (1121); RNA Polymerase Pathway (442); RNA Polymerase, Bacteria Pathway (405267); RNA Polymerase, Bacteria Pathway (468326)
ncbi summary :
HT_Cmplx11_Mem: [More information is available at EcoGene: EG10895]. Along with its partner, the ' subunit of is integrally involved in the enzymatic function of RNA polymerase, especially at the promoter melting stage. [More information is available at EcoCyc: EG10895].
uniprot summary :
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP-Rule MF_01322. Catalytic activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_01322. Subunit structure: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription . By similarity. Sequence similarities: Belongs to the RNA polymerase beta' chain family.
size1 :
0.1 mg
price1 :
380 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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