catalog number :
MBS680012
products full name :
mAb to Sigma 32
products short name :
Sigma 32
products name syn :
MAb to sigma32 (sigma 32) subunit of E.coli RNA polymerase; E. coli RNA Sigma 32 Monoclonal Antibody; SigmaH; rpoH; fam; hin; htpR; Heat shock regulatory protein F33.4
other names :
RNA polymerase, sigma 32 (sigma H) factor; RNA polymerase sigma-32 factor; RNA polymerase, sigma 32 (sigma H) factor; Heat shock regulatory protein F33.4
products gene name :
Sigma 32
other gene names :
rpoH; rpoH; ECK3445; fam; hin; htpR; JW3426; fam; hin; htpR
uniprot entry name :
RP32_ECOLI
sequence positions :
25-Jan
specificity :
Sigma 32 (E. coli Sigma 32)
purity :
Protein G purified
concentration :
1 mg/ml in PBS pH 7.2
storage stability :
Store at -20 degree C lyophilized, 4 degree C Reconstituted, or sub-aliquot and store at -20 degree C
tested application :
Western Blot (WB), ChIP, ELISA (EIA), Transcription Inhibition
app notes :
Immunoprecipitation (IP): Yes, holoenzyme. Transcription Inhibition - Initiation: Yes, in vitro and S-30. Western Blot: Yes - dilute at 1:1000
other info1 :
Immunogen: Recombinant Protein
other info2 :
Reconstitution: Add 100ul of ddH2O to the tube containing antibody and mix to dissolve. Product Note: Cross reactivity and Applications data is per published literature and/or unpublished data
products description :
MAb to sigma 32 subunit of E.coli RNA polymerase. Sigma 32 is a 32 kDA subunit of the E.coli RNA polymerase. Sigma 32 is a 32kDa transcription factor of E.coli RNA polymerase. sigma32 (sigma 32) is a 32kDa subunit of the E.coli RNA polymerase. Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of heat shock promoters.
ncbi gb acc num :
NC_000913.2
ncbi mol weight :
32,469 Da
ncbi summary :
RpoH is phosphorylated at Tyr-260, in HTH DNA-binding region 4.2, attenuating activity. de-phosphorylated by Etp. rpoH can be deleted, but null mutants do not grow above 20C (Zhou, 1988). [More information is available at EcoGene: EG10897]. Sigma 32 is the primary sigma factor controlling the heat shock response during log-phase growth. [More information is available at EcoCyc: EG10897].
uniprot summary :
Function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of heat shock promoters. Sequence similarities: Belongs to the sigma-70 factor family. Sigma-32 subfamily.