catalog number :
MBS673723
products full name :
Rat Anti-Mouse CD102/ICAM-2-UNLB
products short name :
[CD102 (ICAM-2)]
products name syn :
[Rat Anti-Mouse CD102/ICAM-2 - Purified, Unlabeled Antibody; Rat Anti-Mouse CD102 (ICAM-2); ICAM-2, intercellular adhesion molecule-2
]
isotype :
Rat (Lewis) IgG2a kappa
specificity :
Mouse CD102; Mr 55 kDa
form :
UNLB (Unconjugated)
concentration :
0.5 mg/mL
storage stability :
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8°C.
tested application :
Flow Cytometry – Quality tested 1,5. Immunohistochemistry-Frozen Sections – Reported in literature 2,3. Immunocytochemistry – Reported in literature 4,5. Immunoprecipitation – Reported in literature 1. Blocking – Reported in literature 1
app notes :
Flow Cytometry: Purified (UNLB) antibody 6 cells. Since applications vary, you should determine the optimum working dilution for the product that is appropriate for your specific need. References: . 1. Xu H, Bickford JK, Luther E, Carpenito C, Takei F, Springer TA. Characterization of murine intercellular adhesion molecule-2. J Immunol. 1996;156:4909-14. (Immunogen, FC, IP, Block). 2. Cao G, Savani RC, Fehrenbach M, Lyons C, Zhang L, Coukos G, et al. Involvement of endothelial CD44 during in vivo angiogenesis. Am J Pathol. 2006;169:325-36. (IHC-FS). 3. Cao G, Fehrenbach ML, Williams JT, Finklestein JM, Zhu J, DeLisser HM. Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice. Am J Pathol. 2009;175:903-15. (IHC-FS). 4. Shin J, Lee JC, Baek K. A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis. Cancer Lett. 2014;342:70-81. (ICC). 5. Fehrenbach ML, Cao G, Williams JT, Finklestein JM, DeLisser HM. Isolation of murine lung endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2009;296:L1096-1103. (ICC, FC)
image1 heading :
Testing Data
other info1 :
Immunogen: COS cells transfected with mouse ICAM-2 cDNA and BW5147 AKR/J mouse thymoma cell line
other info2 :
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
products description :
The 3C4 monoclonal antibody reacts with the cell surface glycoprotein mouse CD102 (ICAM-2), a ligand for the leucocyte integrin CD11a/CD18 (LFA-1). CD102 is constitutively expressed on T cells, B cells, and at high levels on vascular endothelial cells. It is also expressed on a variety of leukocyte cell lines. The 3C4 antibody blocks the interaction between ICAM-2 and LFA-1.
products references :
1. Xu, H., J.K. Bickford, E. Luther, C. Carpenito, F. Takei, and T.A. Springer. 1996. J. Immunol. 156:4909. 2. Xu, H., O.L. Tong, A.R. deFougerolles, and T.A. Springer. 1992. J. Immunol. 149:2650.