product summary
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company name :
MyBioSource
product type :
secondary antibody
product name :
Mouse Anti-Mouse H-2Kd/H-2Dd-FITC
catalog :
MBS673685
quantity :
0.5 mg
price :
310 USD
more info or order :
product information
catalog number :
MBS673685
products type :
Secondary Antibody
products full name :
Mouse Anti-Mouse H-2Kd/H-2Dd-FITC
products short name :
Mouse (C3H/HeJ) Anti-Mouse H-2Kd/H-2Dd
products name syn :
Mouse Anti-Mouse H-2Kd/H-2Dd - FITC; Mouse (C3H/HeJ) Anti-Mouse H-2Kd/H-2Dd
clonality :
Monoclonal
isotype :
Mouse IgG2a kappa
clone :
34-1-2S
host :
Mouse
reactivity :
Mouse
specificity :
An epitope in the alpha 3 domain that is common to H-2Kd and H-2Dd. The "classical" MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta 2-microglobulin.3,4 These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.5 MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.3,6 The monoclonal antibody 34-1-2S binds to a common determinant in the alpha 3 domains of H-2Kd and H-2Dd in the presence or absence of beta 2 microglobulin.7,8 It cross reacts with the alpha 3 domain of H-2Kb.1,2
form :
Fluorescein (FITC) Conjugate
storage stability :
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! . Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
tested application :
Flow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections)
app notes :
Research Application(s): Complement-mediated cytotoxicity. Flow Cytometry Suggested Dilution: <=1 ug/10^6 cells
other info1 :
Immunogen: C3H alpha BDF1 mouse splenocytes
other info2 :
Characterization: To ensure lot to lot consistency, each batch of product is tested by flow cytometry to conform to characteristics of a standard reference reagent.
products references :
1. Ozato, K., T.H. Hansen, and D.H. Sachs. 1980. J. Immunol. 125:2473. 2. Ozato, K., and D.H. Sachs. 1981. J. Immunol. 126:317. 3. Lawlor, D.A., et al. 1990. Annu. Rev. Immunol. 8:23. 4. Bjorkman, P.J., et al. 1987. Nature 329:506. 5. Yewdell, J.W., and J.R. Bennett. 1990. Cell 62:203. 6. Zijlstra, M., et al. 1990. Nature 344:742. 7. Allen, H., D. Wraith, P. Pala, B. Askonas, and R.A. Flavell. 1984. Nature 309:279. 8. Allen, H, J. Fraser, D. Flyer, S. Calvin, and R. Flavell. 1986. Proc. Natl. Acad. Sci. USA 83:7447
size1 :
0.5 mg
price1 :
310 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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