This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Rat Anti-Mouse IL-17-UNLB
catalog :
MBS670088
quantity :
0.5 mg
price :
320 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
TC11-8H4
reactivity :
human, mouse
product information
catalog number :
MBS670088
products type :
Antibody
products full name :
Rat Anti-Mouse IL-17-UNLB
products short name :
IL-17
products name syn :
Rat Anti-Mouse IL-17 - Purified, Unlabeled Antibody; Rat Anti-Mouse IL-17
other names :
IL-17; Interleukin-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; Cytotoxic T-lymphocyte-associated antigen 8
other gene names :
IL17A; IL17A; IL17; CTLA8; IL-17; IL-17A; CTLA8; IL17; IL-17; IL-17A; CTLA-8
uniprot entry name :
IL17_HUMAN
clonality :
Monoclonal
isotype :
Rat IgG1k
clone :
TC11-8H4
host :
Rat
reactivity :
Mouse
specificity :
Mouse Interleukin-17 (IL-17)
form :
Purified (UNLB) Antibody
storage stability :
The purified (UNLB) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg labeled antibody in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. Reagents are stable for the period shown on the label if stored as directed.
tested application :
ELISA
app notes :
Research Application(s): ELISA Detection: TC11-8H4 monoclonal antibody is useful as a detection antibody in a sandwich ELISA for quantifying mouse IL-17 protein levels. Biotinylated TC11-8H4 antibody should be paired with purified TC11-18H10 antibody as the capture antibody, with purified recombinant mouse IL- 17 as the standard. Since applications vary, each investigator should determine the optimal concentration appropriate for individual applications.
other info1 :
Immunogen: E. coli-expressed recombinant mouse IL-17
other info2 :
Characterization: To ensure acceptable performance, each batch of product is tested in a sandwich ELISA to conform to characteristics of a standard reference reagent.
ncbi gi num :
1155223
ncbi acc num :
AAC50341.1
uniprot acc num :
Q16552
ncbi mol weight :
17,504 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!IL23-mediated Signaling Events Pathway 138000!!IL27-mediated Signaling Events Pathway 137929!!Inflammatory Bowel Disease (IBD) Pathway 842771!!Inflammatory Bowel Disease (IBD) Pathway 842797!!Rheumatoid Arthritis Pathway 200309!!Rheumatoid Arthritis Pathway 200269!!TCR Signaling Pathway 198862
ncbi summary :
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Subunit structure: Homodimer. Ref.8. Subcellular location: Secreted. Tissue specificity: Restricted to activated memory T-cells. Post-translational modification: Found both in glycosylated and nonglycosylated forms. Sequence similarities: Belongs to the IL-17 family.
size :
0.5 mg
price :
320 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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