catalog number :
MBS669040
products full name :
Monoclonal Antibody to CD137 (Clone: ABM3D3.2E8)
products short name :
[CD137]
products name syn :
[Q07011; CD137 Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; T-cell antigen 4-1BB homolog; T-cell antigen ILA]
other names :
[tumor necrosis factor receptor superfamily member 9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily member 9; TNF receptor superfamily member 9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD_antigen: CD137]
products gene name :
[CD137]
products gene name syn :
[TNFRSF9]
other gene names :
[TNFRSF9; TNFRSF9; ILA; 4-1BB; CD137; CDw137; CD137; ILA]
purity :
Purified. Protein G Chromatography
form :
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
storage stability :
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
tested application :
Immunohistochemistry (IHC), FACS, Western Blot (WB)
app notes :
Western blot analysis: 4-6 ug/ml. Immunohistochemical Analysis: 2-4 ug/ml. Facs anaysis: 1-2 ug/10^6
Cells
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Testing Data(TD)
image4 description :
Figure-1: Cell surface staining of PHA stimulated PBMC. Green represents isotype control, red represents Anti-CD137 (MBS669040). 1 ug antibody was used. Goat anti mouse PE was used as secondary antibody.
other info1 :
Antigen: CD137. Immunogen Information: A partial length recombinant protein of CD137 was used as the immunogen for this antibody. Conjugation: Unconjugated
products categories :
Cancer Marker
ncbi acc num :
NP_001552.2
ncbi gb acc num :
NM_001561.5
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Downstream Signaling In Naive CD8+ T Cells Pathway (138018); TCR Signaling Pathway (198862)
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
uniprot summary :
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.