product summary
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company name :
MyBioSource
product type :
antibody
product name :
Monoclonal Antibody to CADM1 (Clone: ABM2A73)
catalog :
MBS668976
quantity :
0.1 mg
price :
290 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
[ABM2A73]
reactivity :
human
application :
western blot, flow cytometry, FACS
more info or order :
image
image 1 :
Figure-1: Intra cellular flowcytometry analysis of CADM1. Anti-CADM1 antibody (Clone: ABM2A73) was tested in A431 cells at 0.5 ug/10^6 cells. Green represents isotype control; red represents anti-CADM1 antibody. Goat anti-mouse PE conjugate was used as secondary antibody.
image 2 :
Western blot analysis of CADM1. Anti- CADM1 antibody (Clone: ABM2A73) was tested at 2 ug/ml 293 lysate.
product information
catalog number :
MBS668976
products type :
Antibody
products full name :
Monoclonal Antibody to CADM1 (Clone: ABM2A73)
products short name :
[CADM1]
products name syn :
[IGSF4, IGSF4A, NECL2, SYNCAM, TSLC1]
other names :
[cell adhesion molecule 1 isoform E; Cell adhesion molecule 1; cell adhesion molecule 1; cell adhesion molecule 1; Immunoglobulin superfamily member 4; IgSF4; Nectin-like protein 2; NECL-2; Spermatogenic immunoglobulin superfamily; SgIgSF; Synaptic cell adhesion molecule; SynCAM; Tumor suppressor in lung cancer 1; TSLC-1]
products gene name :
[CADM1]
other gene names :
[CADM1; CADM1; BL2; ST17; IGSF4; NECL2; RA175; TSLC1; IGSF4A; Necl-2; SYNCAM; sgIGSF; sTSLC-1; synCAM1; IgSF4; NECL-2; SgIgSF; SynCAM; TSLC-1]
clonality :
Monoclonal
isotype :
IgG1, kappa
clone :
[ABM2A73]
host :
Rat
reactivity :
Human
purity :
Protein G purification
form :
Purified
storage stability :
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
tested application :
Flow Cytometry (FC/FACS), Western Blot (WB)
app notes :
Western Blot analysis: 2-4 ug/ml, Flow Cytometry analysis: 0.5-1 ug/ 10^6 cells
image1 heading :
Flow Cytometry (FC/FACS)
image2 heading :
Western blot
other info1 :
Immunogen: A partial length recombinant hCADM1 protein (amino acids 132-211) was used as the immunogen for this antibody.
other info2 :
Content: 100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
products categories :
Immunology
ncbi gi num :
148664211
ncbi acc num :
NP_001091987.1
ncbi gb acc num :
NM_001098517.1
uniprot acc num :
Q9BY67
ncbi pathways :
Adherens Junctions Interactions Pathway (119533); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); Nectin/Necl Trans Heterodimerization Pathway (119534)
uniprot summary :
Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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