catalog number :
MBS664094
products type :
Recombinant Protein
products full name :
Recombinant human cystatin C
products short name :
Cystatin C
other names :
cystatin C; Cystatin-C; cystatin-C; cystatin 3; cystatin-3; gamma-trace; post-gamma-globulin; bA218C14.4 (cystatin C); neuroendocrine basic polypeptide; cystatin C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin
other gene names :
CST3; CST3; ARMD11; N/A
uniprot entry name :
CYTC_HUMAN
form :
Lyophilized from a 0.2 mum filtered solution in 50 mM Tris-HCl, pH 7.6, 150 mM NaCl. Product is recommended to reconstitute with deionized water
storage stability :
At -70 degree C. After reconstitution store at -70 degree C. Avoid repeated freezing and thawing. It is recommended to aliquot the product after reconstitution
app notes :
Calibrator or standard in immunoassays, immunogen for antibody production
other info1 :
Source Note: Expressed in E Coli. Immunological Activity: Immunoreactivity is checked using monoclonal antibodies specific to cystatin C
other info2 :
Analysis: Purity > 95 % (SDS-PAGE).
products description :
Consists of a single polypeptide chain corresponding to mature secreted human cystatin C (120 a.a.r.) without tags. Purified protein may contain additional Met residue at the N-terminus of the molecule.
products references :
Search Cystatin C References from PubMed.
ncbi acc num :
CAA29096.1
ncbi mol weight :
15,799 Da
ncbi pathways :
Amyloids Pathway 366238!!Disease Pathway 530764!!Integrated Pancreatic Cancer Pathway 711360!!Salivary Secretion Pathway 153376!!Salivary Secretion Pathway 153352
ncbi summary :
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein. [provided by RefSeq, Nov 2014]