protein

Calmodulin, human

MBS664083

0.1 mg

265 USD

Protein

Calmodulin, human

Calmodulin

calmodulin; Calmodulin; calmodulin; caM; prepro-calmodulin 3; epididymis secretory protein Li 72; calmodulin 3 (phosphorylase kinase, delta)

CALM3; CALM1; PHKD; PHKD3; HEL-S-72; CALM; CAM; CAM1; CaM

CALM_HUMAN

152

Ion-exchange chromatography followed by gel-filtration.

Lyophilized from protein solution with 2 mM EDTA. Product is recommended to reconstitute with distilled water.

At -20 degree C

Bidegree Chemical and immundegree Chemical investigations.

Source Note: Human brain tissue. Blood samples from tissue donors were tested and found to be negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.

Analysis: Purity > 95 % (native PAGE in reducing conditions with EGTA).

825635

CAA36839.1

P62158

16,838 Da

Activation Of Ca-permeable Kainate Receptor Pathway (161046); Activation Of CaMK IV Pathway (161042); Activation Of Kainate Receptors Upon Glutamate Binding Pathway (161043); Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (161033); Adaptive Immune System Pathway (366160); Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Alzheimer's Disease Pathway (83097)

Calmodulin: a calcium-binding small regulatory protein that mediates the control of a large number of enzymes by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Has four functional calcium-binding domains. Phosphorylation and ubiquitination result in a decreased activity. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 14q32.11. Cellular Component: nucleoplasm; spindle pole; centrosome; sarcomere; growth cone; spindle microtubule; cytoplasm; plasma membrane; extracellular region; cytosol; nucleus; vesicle. Molecular Function: protein domain specific binding; nitric-oxide synthase regulator activity; titin binding; calcium ion binding; protein kinase binding; calcium-dependent protein binding; protein serine/threonine kinase activator activity; protein binding; phospholipase binding; N-terminal myristoylation domain binding; thioesterase binding; type 3 metabotropic glutamate receptor binding; phosphoinositide 3-kinase binding; nitric-oxide synthase binding; adenylate cyclase binding. Biological Process: positive regulation of phosphoprotein phosphatase activity; phototransduction, visible light; inositol phosphate metabolic process; nerve growth factor receptor signaling pathway; pathogenesis; signal transduction; nitric oxide metabolic process; positive regulation of protein amino acid dephosphorylation; synaptic transmission; platelet degranulation; substantia nigra development; muscle contraction; positive regulation of cyclic nucleotide metabolic process; response to corticosterone stimulus; epidermal growth factor receptor signaling pathway; platelet activation; mitochondrion organization and biogenesis; glycogen catabolic process; fibroblast growth factor receptor signaling pathway; regulation of heart rate; positive regulation of nitric-oxide synthase activity; organelle organization and biogenesis; response to amphetamine; adenylate cyclase activation; glucose metabolic process; regulation of cytokinesis; positive regulation of protein amino acid autophosphorylation; rhodopsin mediated signaling; G-protein coupled receptor protein signaling pathway; regulation of rhodopsin mediated signaling; phospholipase C activation; carbohydrate metabolic process; innate immune response; positive regulation of cyclic-nucleotide phosphodiesterase activity; detection of calcium ion; regulation of nitric-oxide synthase activity; response to calcium ion; blood coagulation; vascular endothelial growth factor receptor signaling pathway. Disease: Long Qt Syndrome 14; Ventricular Tachycardia, Catecholaminergic Polymorphic, 4

0.1 mg

265 USD

0.5 mg

405

1 mg

535