catalog number :
MBS662002
products full name :
Polyclonal anti-cardiac Troponin T (cTnT)
products short name :
Troponin T cardiac
other names :
troponin T, cardiac muscle; Troponin T, cardiac muscle; troponin T, cardiac muscle; cTnT; tnTc; Troponin T cardiac; cardiac troponin T2; troponin T2, cardiac; cardiac muscle troponin T; troponin T type 2 (cardiac); Cardiac muscle troponin T; cTnT
products gene name :
cTnT
other gene names :
Tnnt2; Tnnt2; Ctt; CTTG; Tnnt3; RATCTTG; TnTc; cTnT
uniprot entry name :
TNNT2_RAT
specificity :
Human cardiac troponin T
purity :
Immunoaffinity method utilizing cTnT-agarose as an affinity matrix.
form :
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
storage stability :
4 degree C
tested application :
Immunoprecipitation (IP), Immunohistdegree Chemistry (IHC), Western Blot (WB)
app notes :
Human cardiac troponin T immunoassay, immunoprecipitation, immunohistdegree Chemistry, Western blotting
other info1 :
Immunogen: Human cardiac troponin T, purity more than 98%
ncbi acc num :
NP_036808.1
ncbi gb acc num :
NM_012676.1
ncbi mol weight :
34,452 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway (908278); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Cardiac Muscle Contraction Pathway (93346); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121476); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114014); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Muscle Contraction Pathway (1121504); Striated Muscle Contraction Pathway (1121505)
ncbi summary :
tropomyosin-binding subunit of troponin; confers calcium-sensitivy to actinomysin ATPase activity in striated muscle [RGD, Feb 2006]
uniprot summary :
TNNT2: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart. Belongs to the troponin T family. 11 isoforms of the human protein are produced by alternative splicing. Protein type: Motor; Motility/polarity/chemotaxis. Cellular Component: sarcomere; troponin complex; myofibril; cytoplasm; striated muscle thin filament. Molecular Function: protein binding, bridging; troponin C binding; structural constituent of cytoskeleton; troponin I binding; ATPase activity; tropomyosin binding; actin binding. Biological Process: actin crosslink formation; regulation of muscle contraction; atrial cardiac muscle morphogenesis; protein heterooligomerization; metabolic process; heart development; regulation of muscle filament sliding speed; sarcomere organization; regulation of heart contraction; muscle filament sliding; muscle contraction; positive regulation of ATPase activity; ventricular cardiac muscle morphogenesis; response to calcium ion; negative regulation of ATPase activity; cardiac muscle contraction