catalog number :
MBS660234
products full name :
Monoclonal mouse anti-Hemoglobin human HbA10
products short name :
Hemoglobin human HbA10
other names :
hemoglobin, partial; Hemoglobin subunit beta; hemoglobin subunit beta; beta globin chain; hemoglobin beta chain; hemoglobin, beta; Beta-globin; Hemoglobin beta chainCleaved into the following 2 chains:LVV-hemorphin-7; Spinorphin
products gene name :
HbA10
other gene names :
HBB; HBB; CD113t-C; beta-globin
uniprot entry name :
HBB_HUMAN
isotype :
IgG1 for MAbs Hb4 and Hb6
purity :
Chromatography on protein A Sepharose
form :
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
storage stability :
4 degree C
app notes :
HbA1c immunoassay.
other info1 :
Clone Note: Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with glycated (in vitro) synthetic peptide corresponding to the N-terminal end of beta-globin.
ncbi acc num :
ABG47031.1
ncbi mol weight :
15,998 Da
ncbi pathways :
African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway 645347!!Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway 645348!!Factors Involved In Megakaryocyte Development And Platelet Production Pathway 187196!!Folate Metabolism Pathway 198833!!Hemostasis Pathway 106028!!Malaria Pathway 152665!!Malaria Pathway 152657
ncbi summary :
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]