product summary
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company name :
MyBioSource
product type :
antibody
product name :
Monoclonal mouse anti-human alpha-fetoprotein
catalog :
MBS660053
quantity :
1 mg
price :
365 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5H7
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS660053
products type :
Antibody
products full name :
Monoclonal mouse anti-human alpha-fetoprotein
products short name :
a-Fetoprotein
other names :
alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-fetoglobulin; alpha-1-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
other gene names :
AFP; AFP; AFPD; FETA; HPAFP; HPAFP
uniprot entry name :
FETA_HUMAN
clonality :
Monoclonal
isotype :
IgG1 for MAb 5H7
clone :
5H7
sequence length :
609
specificity :
MAbs react with different determinants of human alpha-fetoprotein. MAbs do not cross-react with human albumin.
purity :
Chromatography on protein A Sepharose
form :
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
concentration :
3.4mg/ml
storage stability :
4 degree C (2 degree C - 8 degree C also allowed)
app notes :
We recommend the following pair in sandwich immunoassay (capture - detection): 4A3 - 5H7
other info1 :
Volume: 2 x 0.295ml. Clone Note: Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified human alpha-fetoprotein.
other info2 :
Material Safety Note: Product contians sodium azide as preservative. Although the amounth of sodium azide is very small appropriate care must be taken when handling this product.
ncbi gi num :
4501989
ncbi acc num :
NP_001125.1
ncbi gb acc num :
NM_001134.2
ncbi mol weight :
68,678 Da
ncbi pathways :
Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
uniprot summary :
AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cytoplasm. Molecular Function: metal ion binding. Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of
size1 :
1 mg
price1 :
365 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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