protein

Somatostatin 28 (Biotin)

MBS659867

1 mg

520 USD

Peptide

Somatostatin 28 (Biotin)

[Somatostatin 28]

[somatostatin preproprotein; Somatostatin; somatostatin; somatostatin-14; somatostatin-28; prepro-somatostatin; growth hormone release-inhibiting factor; somatostatin; Growth hormone release-inhibiting factor]

[SST; SST; SMST]

SMS_HUMAN

Bioti n-Ser -Ala-Asn-Ser -Asn-Pro-Ala-M et -Ala -Pro-Arg-G IU-Arg-L ys-Ala-G Iy-C ys-L yS-As nPhe- Phe-T rp-L ys-Th r -Phe-Th r -Ser -C ys

~95%. Purified by HPLC.

Supplied as a lyophilized powder

Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Source: Synthetic peptide. Molecular Formula: 97.80%

Molecular Biology; MB-Peptides

4507243

NP_001039.1

NM_001048.3

P61278

3376.93

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Peptide Ligand-binding Receptors Pathway (106358); SIDS Susceptibility Pathways (198901); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

Function: Somatostatin inhibits the release of somatotropin. Subcellular location: Secreted. Pharmaceutical use: A synthetic analog known as octreotide or SMS 201-995 is available under the name Sandostatin (Novartis). It is used for the treatment of a variety of disorders including acromegaly and the symptomatic treatment of carcinoid tumors and vasoactive intestinal peptide tumors. Sequence similarities: Belongs to the somatostatin family.

1 mg

520 USD