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Galanthus nivalis (Snowdrop bulb) (GNA) (Biotin)

MBS656128

1 mg

345 USD

Lectin

Galanthus nivalis (Snowdrop bulb) (GNA) (Biotin)

[Galanthus nivalis]

Galanthus nivalis (snowdrop bulb)

Highly purified. Three bands at 26kD, 30kD and 44kD detected by SDS-PAGE.

Supplied as a liquid in PBS, pH 7.2-7.4. Labeled with biotin.

1 mg/ml

May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunohistochemistry (IHC)

Isoelectric Point: < pH 4.6

Inhibitory Carbohydrate: Mannose a-1,3-mannose, Mannose. Carbohydrate Specificity: Mannose. Activity (unconjugated): less than or equal to 15ug/ml will agglutinate human type O erythrocytes.

Lectins; Lectin-Galanthus nivalis

Galanthus nivalis agglutinin (GNA) is a small molecular weight tetramer consisting of subunits of about 13,000D. This lectin contains little or no carbohydrate. Unlike most mannose-specific lectins, it is not a metalloprotein and does not require Ca++ or Mn++ for binding. Binding seems to be preferentially directed toward structures containing (a-1,3) mannose residues. In contrast to most mannose-binding lectins, GNA will not bind alpha linked glucose. Reports indicate that this lectin binds IgM, but not bind IgG immunoglobulin classes of rat and mouse. The only protein from human serum reported to bind to this lectin is a2-macroglobulin.

110kD

1 mg

345 USD