catalog number :
MBS651035
products type :
Recombinant Protein
products full name :
Interleukin 6, Recombinant, Human (IL-6, B cell Stimulatory Factor 2, BSF2, Cytotoxic T cell Differentiation Factor, CTL Differentiation Factor, CDF, Hepatocyte Stimulating Factor, HSF, Hybridoma Growth Factor, HGF, Hybridoma Plasmacytoma Growth Factor, H
products short name :
Interleukin 6
products name syn :
Interleukin 6, Recombinant, Human (IL-6, B cell Stimulatory Factor 2, BSF2, Cytotoxic T cell Differentiation Factor, CTL Differentiation Factor, CDF, Hepatocyte Stimulating Factor, HSF, Hybridoma Growth Factor, HGF, Hybridoma Plasmacytoma Growth Factor, H
other names :
interleukin-6; Interleukin-6; interleukin-6; IL-6; Interleukin 6 (interferon, beta 2); interleukin 6; N/A
other gene names :
Il6; Il6; ILg6; Ifnb2; Il-6
uniprot entry name :
IL6_RAT
purity :
Highly Purified. 95% as determined by SDS-PAGE and HPLC.
form :
Supplied as a lyophilized powder from 20mM Tris, pH 7.4, 150mM NaCl. Reconstitute with sterile dH2O, 0.1% endotoxin-free recombinant HSA.
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS, 0.1% HSA (A1327-54A). Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
other info1 :
Activity: The specific activity was determined by the dose-dependent stimulation of the proliferation. of human TF-1 cells (human erythroleukemic indicator cell line). Specific Activity: ~0.2-1ng/ml ED50. Endotoxin Level: 1EU/ug (LAL)
products categories :
Growth Factors, Cytokines; Growth Factors-Interleukin
ncbi acc num :
NP_036721.1
ncbi gb acc num :
NM_012589.1
ncbi mol weight :
26-30kD
ncbi pathways :
Adipogenesis Pathway 198479!!African Trypanosomiasis Pathway 194377!!African Trypanosomiasis Pathway 194323!!Amoebiasis Pathway 167311!!Amoebiasis Pathway 167191!!Androgen Receptor Signaling Pathway 198529!!Chagas Disease (American Trypanosomiasis) Pathway 147806!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Cytokine-cytokine Receptor Interaction Pathway 83443!!Cytokine-cytokine Receptor Interaction Pathway 460
ncbi summary :
a cytokine involved in development and possibly in neurodegenerative processes [RGD]
uniprot summary :
Function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. Subcellular location: Secreted. Sequence similarities: Belongs to the IL-6 superfamily.