product summary
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company name :
MyBioSource
product type :
protein
product name :
Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF)
catalog :
MBS650808
quantity :
0.1 mg
price :
505 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS650808 image 1
15% SDS-PAGE of I8442-43A (3ug)
product information
catalog number :
MBS650808
products type :
Recombinant Protein
products full name :
Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF)
products short name :
[Interleukin 32, 1-131aa]
other names :
[Interleukin 32; Interleukin-32; interleukin-32; OTTHUMP00000236040; OTTHUMP00000236041; OTTHUMP00000236042; OTTHUMP00000236043; OTTHUMP00000236044; OTTHUMP00000236045; OTTHUMP00000236046; OTTHUMP00000236047; OTTHUMP00000236048; OTTHUMP00000236049; OTTHUMP00000236050; OTTHUMP00000236051; OTTHUMP00000236052; OTTHUMP00000236053; OTTHUMP00000236054; interleukin-32 theta; natural killer cells protein 4; natural killer cell transcript 4; tumor necrosis factor alpha-inducing factor; interleukin 32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor]
other gene names :
[IL32; IL32; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma; NK4; TAIF]
uniprot entry name :
IL32_HUMAN
sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCF PKVLSDDMKK LKARMHQAIE RFYDKMQNAE SGRGQVMSSL AELEDDFKEG YLETVAAYYE EQHPELTPLL EKERDGLRCR GNRSPVPDVE DPATEEPGES FCDKSYGAPR GDKEELTPQK CSEPQSSK
purity :
>95% (SDS-PAGE)
form :
Supplied as a liquid in 20mM Tris-HCl, pH8.0, 1mM DTT, 10% glycerol.
concentration :
1mg/ml
storage stability :
May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
image1 heading :
SDS-Page
other info1 :
Endotoxin: <1EU/1ug (LAL)
products categories :
Growth Factors, Cytokines; Growth Factors-Interleukin
products description :
Interleukin 32 isoform A belongs to cytokine family. This protein expression is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. It has the ability to induce proinflammatory cytokines such as TNF_ and IL8 in THP1 cells, and activates typical cytokine signaling pathways involving NF_B and p38. IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton. Recombinant protein corresponding to aa1-131 of human of human interleukin 32, fused to His-tag at N-terminus, was expressed in E.coli.
ncbi gi num :
111493923
uniprot acc num :
P24001
ncbi mol weight :
19.1kD (168aa)
ncbi summary :
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
uniprot summary :
Function: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. Ref.2. Subcellular location: Secreted Ref.2. Tissue specificity: Selectively expressed in lymphocytes. Expression more prominent in immunce cells than in non-immune cells. Ref.2. Induction: Expression increased after activation of T-cells by mitogens or activation of NK cells by IL2/interleukin-2. Ref.1
size1 :
0.1 mg
price1 :
505 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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