catalog number :
MBS646897
products full name :
PLBD1 (Phospholipase B-like 1, LAMA-like Protein 1, Lamina Ancestor Homolog 1, Phospholipase B Domain-containing Protein 1, FLJ22662)
products short name :
[PLBD1]
products name syn :
[Anti -PLBD1 (Phospholipase B-like 1, LAMA-like Protein 1, Lamina Ancestor Homolog 1, Phospholipase B Domain-containing Protein 1, FLJ22662)]
other names :
[PLBD1 protein; Phospholipase B-like 1; phospholipase B-like 1; PLB homolog 1; LAMA-like protein 1; lamina ancestor homolog 1; putative phospholipase B-like 1; phospholipase B domain-containing protein 1; phospholipase B domain containing 1; LAMA-like protein 1; Lamina ancestor homolog 1; Phospholipase B domain-containing protein 1]
other gene names :
[PLBD1; PLBD1]
uniprot entry name :
PLBL1_HUMAN
sequence :
MMADSGKRWADIFSKYNSGTYNNQYMVLDLKKVKLNHSL
DKGTLYIVEQIPTYVEYSEQTDVLRKGYWPSYNVPFHEK
IYNWSGYPLLVQKLGLDYSYDLAPRAKIFRRDQGKVTDT
ASMKYIMRYNNYKKDPYSRGDPCNTICCREDLNSPNPSP
GGCYDTKVADIYLASQYTSYAISGPTVQGGLPVFRWDRF
NKTLHQGMAEVYNFDFITMKPILKLDIK
specificity :
Recognizes human PLBD1
purity :
Affinity Purified. Purified by Protein A affinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.4.
storage stability :
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Western Blot (WB). Other applications not tested.
app notes :
Optimal dilutions to be determined by the researcher.
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Full length protein corresponding to aa 1-223 of human PLBD1
products categories :
Antibodies; Abs to Enzymes, Phospholipase
products description :
Phospholipase acting on various phospholipids including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids. May have a role in the defense against invading microorganisms and in the generation of lipid mediators of inflammation.
ncbi pathways :
Acyl Chain Remodelling Of PC Pathway (645321); Acyl Chain Remodelling Of PE Pathway (645317); Acyl Chain Remodelling Of PI Pathway (645326); Glycerophospholipid Biosynthesis Pathway (645313); Hydrolysis Of LPC Pathway (645322); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Phospholipid Metabolism Pathway (645312)
uniprot summary :
Function: Phospholipase acting on various phospholipids including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids. May have a role in the defense against invading microorganisms and in the generation of lipid mediators of inflammation. Ref.4. Subunit structure: May exist as a non-covalently associated tetramer of two 22 kDa and two 42 kDa chains. Ref.4. Subcellular location: Cytoplasmic granule. Secreted Ref.4. Tissue specificity: Expressed in neutrophils and monocytes. Ref.4. Post-translational modification: Proteolytic processing leading to a 22 kDa N-terminal and a 42 kDa C-terminal fragment appears necessary for activity, which seems to derive from the 42 kDa chain. Sequence similarities: Belongs to the phospholipase B-like family. Biophysicochemical propertiespH dependence:Optimum pH is 7.4. Ref.4. Sequence caution: The sequence AAH00909.2 differs from that shown. Reason: Erroneous initiation. The sequence BAB15442.1 differs from that shown. Reason: Erroneous initiation.