catalog number :
MBS644934
products full name :
SELT, NT (SELT, Selenoprotein T)
products short name :
[SELT]
products name syn :
[Anti -SELT, NT (SELT, Selenoprotein T)]
other names :
[selenoprotein T; Selenoprotein T; selenoprotein T]
other gene names :
[SELT; SELT; SelT]
uniprot entry name :
SELT_HUMAN
specificity :
Specific human SELT
purity :
Purified by Protein A and peptide affinity chromatography.
form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
concentration :
0.59 mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
app notes :
Western Blot: 1:1000. Flow Cytometry: 10:10-1:50. Optimal dilutions to be determined by the researcher.
image1 heading :
Western Blot (WB)
image2 heading :
Flow Cytometry (FC/FACS)
other info1 :
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 48-75 in the N-terminal region of human SELT. Species Sequence Homology: Bovine , chicken, mouse and rat
other info2 :
Grade: Affinity Purified
products categories :
Antibodies; Abs to Selenoprotein
products description :
SELT encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
ncbi acc num :
NP_057359.2
ncbi gb acc num :
NM_016275.3
ncbi pathways :
Selenium Metabolism And Selenoproteins Pathway (198846); Selenium Pathway (198825)
ncbi summary :
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
uniprot summary :
SELT: a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 3q25.1. Molecular Function: selenium binding. Biological Process: cell redox homeostasis; selenocysteine incorporation