TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15) | MyBioSource MBS644796 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15)

catalog :

MBS644796

quantity :

0.2 mL

price :

500 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS644796

products type :

Antibody

products full name :

TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15)

products short name :

TCEB1

products name syn :

Anti -TCEB1, CT (TCEB1, Transcription elongation factor B polypeptide 1, Elongin 15kD subunit, Elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15)

other names :

transcription elongation factor B polypeptide 1 isoform b; Transcription elongation factor B polypeptide 1; transcription elongation factor B polypeptide 1; SIII p15; elongin 15 kDa subunit; RNA polymerase II transcription factor SIII subunit C; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); Elongin 15 kDa subunit; Elongin-C; EloC; RNA polymerase II transcription factor SIII subunit C; SIII p15

other gene names :

TCEB1; TCEB1; SIII; eloC; EloC

uniprot entry name :

ELOC_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

specificity :

Recognizes human TCEB. Species Sequences Homology: bovine, mouse and rat.

purity :

Affinity Purified. Purified by Protein A affinity chromatography.

form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

concentration :

0.5mg/ml

storage stability :

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

tested application :

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Suitable for use in Western Blot, Immunohistochemistry, ELISA. Dilution: . Western Blot: 1:1000. Immunohistochemistry: 1:10-50. Optimal dilutions to be determined by the researcher.

other info1 :

Immunogen: TCEB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the C-terminal region of human TCEB1. UniProt Accession #: NP_005639.1; Q15369; P83941; P83940; Q2K114.

products categories :

Antibodies; Abs to Transcription Factors

products description :

This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

ncbi gi num :

325652048

ncbi acc num :

NP_001191793.1

ncbi gb acc num :

NM_001204864.1

uniprot acc num :

Q15369

ncbi pathways :

Adaptive Immune System Pathway (366160); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (366162); Cellular Response To Hypoxia Pathway (645259); Cellular Responses To Stress Pathway (645258); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Disease Pathway (530764); ECS Complex Pathway (413455); ECS Complex Pathway (468394); ECV Complex Pathway (413450); Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway (161052)

ncbi summary :

uniprot summary :

TCEB1: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). Belongs to the SKP1 family. Protein type: Transcription initiation complex. Chromosomal Location of Human Ortholog: 8q21.11. Cellular Component: nucleoplasm; VCB complex; cytosol. Molecular Function: protein binding; protein complex binding. Biological Process: transcription from RNA polymerase II promoter; ubiquitin-dependent protein catabolic process; regulation of transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; positive regulation of RNA elongation from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; gene expression

size1 :

0.2 mL

price1 :

500 USD

more info or order :

MyBioSource product webpage