antibody

NMDA Receptor NR1, Splice Variant N1 (N-methyl-D-aspartate Receptor Subunit NR1, NMD-R1, NMDAR1, Nmdar, NR1, Glutamate [NMDA] Receptor Subunit zeta-1, Grin1, GluRdelta1, GluRzeta1, Glurz1, M100174, Rgsc174)

MBS642225

0.025 mg

775 USD

polyclonal

rabbit

nonconjugated

western blot, immunohistochemistry

Antibody

NMDA Receptor NR1, Splice Variant N1 (N-methyl-D-aspartate Receptor Subunit NR1, NMD-R1, NMDAR1, Nmdar, NR1, Glutamate [NMDA] Receptor Subunit zeta-1, Grin1, GluRdelta1, GluRzeta1, Glurz1, M100174, Rgsc174)

[NMDA Receptor NR1, Splice Variant N1]

[Anti -NMDA Receptor NR1, Splice Variant N1 (N-methyl-D-aspartate Receptor Subunit NR1, NMD-R1, NMDAR1, Nmdar, NR1, Glutamate [NMDA] Receptor Subunit zeta-1, Grin1, GluRdelta1, GluRzeta1, Glurz1, M100174, Rgsc174)]

Polyclonal

IgG

Rabbit

Rat

Recognizes rat NMDA Receptor 1, N1.

Serum. Serum

Supplied as a lyophilized powder from 5mM ammonium bicarbonate. Reconstitute with 50ul PBS, pH 7.4.

~0.5mg/ml

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB), Immunohistochemistry (IHC)

Suitable for use in Immunohistochemistry and Western Blot. Dilution: Immunohistochemistry: 1:1000. Western Blot: 1:1000-1:2000, ~100kD band in rat hippocampal homogenate

Western Blot (WB)

Immunogen: Peptide corresponding to N1 splice variant of NMDA Receptor 1.

Antibodies; Abs to Ion Channel

N-methyl-D-aspartate receptor (NMDAR) forms a heterodimer of at least one NR1 and one NR2A-D subunit. Multiple receptor isoforms with distinct brain distributions and functional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2 subunits. NR1 subunits bind the co-agonist glycine and NR2 subunits bind the neurotransmitter glutamate. NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

0.025 mg

775 USD