HBG1, ID (HBG1, Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain) | MyBioSource MBS642015 product information

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company name :

MyBioSource

product type :

antibody

product name :

HBG1, ID (HBG1, Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain)

catalog :

MBS642015

quantity :

0.2 mL

price :

610 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot analysis of HBG1 (arrow) on 293 cell lysates (2ug/lane) using MBS642015. Lane 1: nontransfected Lane 2: transiently transfected with the HBG1 gene.

image 2 :

Western Blot analysis in K562 cell line lysates (35ug/lane) using MBS642015. This demonstrates that MBS642015 detected the HBG1 protein (arrow).

product information

catalog number :

MBS642015

products type :

Antibody

products full name :

HBG1, ID (HBG1, Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain)

products short name :

[HBG1]

products name syn :

[Anti -HBG1, ID (HBG1, Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain)]

other names :

[hemoglobin subunit gamma-1; Hemoglobin subunit gamma-1; hemoglobin subunit gamma-1; hb F Agamma; gamma globin; A-gamma globin; gamma-1-globin; gamma A hemoglobin; hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin, gamma, regulator of; hemoglobin, gamma A; Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain]

other gene names :

[HBG1; HBG1; HBGA; HBGR; HSGGL1; PRO2979]

uniprot entry name :

HBG1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

specificity :

Human HBG1

purity :

Purified by Protein A and peptide affinity chromatography.

form :

Supplied as a liquid in PBS, 0.09% sodium azide.

concentration :

0.5 mg/ml

storage stability :

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

tested application :

Western Blot (WB), ELISA

app notes :

Suitable for use in Western Blot and ELISA. Other applications not tested. Western Blot: 1:1000. Optimal dilutions to be determined by the researcher.

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

other info1 :

Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 56-85 in the central region of human HBG1.

products categories :

Antibodies; Abs to Hemoglobin

products description :

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

ncbi gi num :

28302131

ncbi acc num :

NP_000550.2

ncbi gb acc num :

NM_000559.2

uniprot acc num :

P69891

ncbi mol weight :

16,140 Da

ncbi summary :

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

uniprot summary :

HBG1: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Belongs to the globin family. Protein type: Carrier. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: hemoglobin complex; cytosol. Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity. Biological Process: oxygen transport; blood coagulation. Disease: Fetal Hemoglobin Quantitative Trait Locus 1

size1 :

0.2 mL

price1 :

610 USD

more info or order :

MyBioSource product webpage