product summary
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company name :
MyBioSource
product type :
protein
product name :
IL-36 alpha, Recombinant, Mouse (Interleukin-36alpha, Interleukin-1 Family Member 6, IL-1F6, FIL1epsilon, Interleukin-1epsilon, Interleukin-1 Homolog 1, IL-1H1)
catalog :
MBS638329
quantity :
0.01 mg
price :
460 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS638329
products type :
Recombinant Protein
products full name :
IL-36 alpha, Recombinant, Mouse (Interleukin-36alpha, Interleukin-1 Family Member 6, IL-1F6, FIL1epsilon, Interleukin-1epsilon, Interleukin-1 Homolog 1, IL-1H1)
products short name :
IL-36 alpha
other names :
interleukin-36 alpha; Interleukin-36 alpha; interleukin-36 alpha; FIL1 epsilon; IL-1 epsilon; interleukin-1 epsilon; IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; interleukin-1 family member 6; interleukin 1 family, member 6 (epsilon); interleukin 36, alpha; FIL1 epsilon; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 6
other gene names :
IL36A; IL36A; FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON); FIL1E; IL1E; IL1F6; IL-1 epsilon; IL-1F6
uniprot entry name :
IL36A_HUMAN
host :
Mouse, E Coli
sequence :
IL-36alpha (mouse) (aa 8-160) is untagged.
purity :
Highly Purified. >=95% (SDS-PAGE)
form :
Supplied as a lyophilized powder from PBS. Rconsitute with 100 ul sterile ddH2O.
concentration :
~0.1mg/ml (after reconstitution)
storage stability :
Lyophilized powder may be stored at -20 degree C. Stable for 12 months after receipt at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at - 20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
other info1 :
Biological Activity: Induces secretion of IL-6 in BMDCs at a concentration of 100ng - 1ug/ml. Endotoxin: <0.01EU/ug
products categories :
Growth Factors, Cytokines; Growth Factors-Interleukin
products description :
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
ncbi gi num :
7657092
ncbi acc num :
NP_055255.1
ncbi gb acc num :
NM_014440.1
uniprot acc num :
Q9UHA7
ncbi mol weight :
~17kD
uniprot summary :
IL1F6: Belongs to the IL-1 family. Protein type: Cytokine. Chromosomal Location of Human Ortholog: 2q12-q14.1. Cellular Component: extracellular space; extracellular region. Molecular Function: interleukin-1 receptor binding; cytokine activity. Biological Process: cytokine and chemokine mediated signaling pathway; innate immune response; positive regulation of interleukin-6 production; immune response; inflammatory response
size1 :
0.01 mg
price1 :
460 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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