catalog number :
MBS637397
products type :
Recombinant Protein
products full name :
Interleukin 1 beta, aa118-269, Recombinant, Mouse, His tag (IL1b, IL-1 beta, Catabolin, Hematopoietin 1, H1, IFN beta Inducing Factor, IL1F2, LAF, OAF, Osteoclast Activating Factor, Preinterleukin beta, Pro Interleukin 1 beta)
products short name :
[Interleukin 1 beta, aa118-269, His tag]
other names :
[interleukin 1, beta; interleukin 1, beta; interleukin-1-beta; interleukin 1, beta]
other gene names :
[il1b; IL-1; IL-1B; il1b-A]
sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMVPI RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS TSQAEHKPVF LGNNSGQDII DFTMESVSS
purity :
>90% by SDS PAGE
form :
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol
storage stability :
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
image1 heading :
SDS-Page
products categories :
Growth Factors, Cytokines; Growth Factors-Interleukin
products description :
IL-1 beta is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1 beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1 beta is required for tumor growth, metastasis, and angiogenesis in several animal models. Recombinant protein corresponding to aa118-269 with a His-Tag from mouse Interleukin 1 beta, expressed in E. coli. Purified by using conventional chromatography techniques.
ncbi gb acc num :
NM_001085605.1
ncbi pathways :
Apoptosis Pathway (84655); Apoptosis Pathway (470); Cytokine-cytokine Receptor Interaction Pathway (119282); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125125); Cytosolic DNA-sensing Pathway (124833); Herpes Simplex Infection Pathway (377871); Herpes Simplex Infection Pathway (377865); MAPK Signaling Pathway (84645); MAPK Signaling Pathway (456)