product summary
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company name :
MyBioSource
product type :
protein
product name :
Paraoxonase 1, Recombinant, Human (Serum Paraoxonase/Arylesterase 1, PON 1, Aromatic Esterase 1, A-esterase 1, K-45, Serum Aryldialkylphosphatase 1, PON, PON1)
catalog :
MBS637128
quantity :
1 mL
price :
565 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS637128 image 1
Assay Conditions: Paraoxonase-1 catalyses the cleavage of phenyl acetate (4 mM) in 20mM Tris HCl buffer pH 8, containing 1mM CaCl2 resulting in phenol formation. The rate of formation of phenol is measured by monitoring the increase in absorbance at 270nm at 25 C. One unit of arylesterase activity is equal to 1uM of phenol formed per minute. The activity is expressed in kU/L, based on the extinction coefficient of phenol of 1310 M-1 cm at 270nm, pH 8, and 25 C.
product information
catalog number :
MBS637128
products type :
Recombinant Protein
products full name :
Paraoxonase 1, Recombinant, Human (Serum Paraoxonase/Arylesterase 1, PON 1, Aromatic Esterase 1, A-esterase 1, K-45, Serum Aryldialkylphosphatase 1, PON, PON1)
products short name :
[Paraoxonase 1]
other names :
[paraoxonase 1]
purity :
Purified
form :
Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 75mM sodium chloride, 0.05% Triton, 50% glycerol
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
image1 heading :
Testing Data
other info1 :
Source: Recombinant corresponding to human PON1, fused to 6X His-tag at C-terminal, expressed in CHO-K1 cells. Activity: 13.87U/ml
products categories :
Molecular Biology; MB-Enzymes, Phosphatase
products description :
Paraoxonase-1 is involved in the detoxification of organophosphate insecticides such as parathion. Paraoxonase-1 may also confer protection against coronary artery disease by destroying pro-inflammatory oxidized lipids present in oxidized low-density lipoproteins (LDL's).
ncbi gi num :
345894407
ncbi acc num :
AEO20077.1
ncbi summary :
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq, Oct 2008]
size1 :
1 mL
price1 :
565 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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