protein

HIV-2 gp36, Recombinant, soluble (Human Immunodeficiency Virus-2)

MBS636851

1 mg

540 USD

Recombinant Protein

HIV-2 gp36, Recombinant, soluble (Human Immunodeficiency Virus-2)

[HIV-2 gp36, soluble]

E Coli

Human

>=90%

Supplied as a liquid in 20mM carbonate buffer, pH 9.6, 0.1% sodium azide.

5.51 mg/mL

May be stored at 4°C for short term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C . For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Suitable for use in ELISA (EIA). Other applications not tested.

Suitable for use in ELISA.

Molecular Biology; MB-Infectious Disease

HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response.

1 mg

540 USD