catalog number :
MBS636718
products type :
Recombinant Protein
products full name :
SSAT-1, Recombinant Human (AA617398, Diamine acetyltransferase 1, Polyamine N-acetyltransferase 1, Putrescine acetyltransferase, Sat, Spermidine/spermine N(1)-acetyltransferase 1, SSAT, SSAT-1, DC21, KFSD, KFSDX)
products short name :
SSAT-1 Human
other names :
spermidine/spermine N1-acetyltransferase; spermidine/spermine N1-acetyltransferase; ssat1c; spermidine/spermine N1-acetyltransferase 1; spermidine/spermine N1-acetyltransferase 1a, duplicate 2
other gene names :
sat1a.2; SSAT-1; bZ1F1.2; zgc:91957
sequence :
MGSSHHHHHH SSGLVPRGSH MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS EEGWRLFKID. KEYLLKMATE E
purity :
>95% by SDS-PAGE. Purified by immunoaffinity chromatography.
form :
Supplied as liquid in 20 mM Tris-HCl buffer, pH8.0, 10% glycerol
storage stability :
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
Dilutions: Optimal dilutions to be determined by the researcher.
app notes :
Suitable for use in ELISA and Western Blot.
products categories :
Molecular Biology; MB-Enzymes, Acetyltransferase
products description :
Diamine N-acetyltransferase 1(or Spermidine/spermine-N1-acetyltransferase, SSAT1), as known as SAT-1, is a polyamine catabolic enzyme which catalyzes the acetylation of polyamines. This protein plays an important role in polyamine homoeostasis, since acetylated products are either excreted from the cell or oxidized by acetylpolyamine oxidase. A variety of other effects of increased SAT-1 activity include death of pancreatic cells, blockage of regenerative tissue growth, behavioral changes, keratosis follicularis spinulosa decalvans(KFSD), and hair loss. Recombinant protein corresponding to aa1-171 of human Diamine N-acetyltransferase 1 fused to His-tag at the N-Terminal, expressed in E.coli.
ncbi acc num :
NP_001002169.1
ncbi gb acc num :
NM_001002169.1
ncbi pathways :
Arginine And Proline Metabolism Pathway (83543); Arginine And Proline Metabolism Pathway (323); GABA Biosynthesis, Eukaryotes, Putrescine = GABA Pathway (401514); GABA Biosynthesis, Eukaryotes, Putrescine = GABA Pathway (468314)