product summary
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company name :
MyBioSource
product type :
protein
product name :
LEPR, Recombinant, Human (Leptin Receptor, LEP-R, HuB219, OB Receptor, OB-R, CD295, DB, OBR)
catalog :
MBS636524
quantity :
0.01 mg
price :
410 USD
more info or order :
product information
catalog number :
MBS636524
products type :
Recombinant Protein
products full name :
LEPR, Recombinant, Human (Leptin Receptor, LEP-R, HuB219, OB Receptor, OB-R, CD295, DB, OBR)
products short name :
LEPR
other names :
LEPR
host :
Human Cells
sequence :
A DNA sequence encoding the extracellular domian (Met 1-Asp 839) of human leptin receptor (Np_002294.2) was expressed and fused with a C-terminal polyhistidine tag. Predict NT sequence is Phe 22.
specificity :
Leptin, LERP is expressed at high levels in hematopoietic stem cells, lymphohematopoietic cell lines, as well as adult reproductive organs. Several isoforms of LEPR have been identified, and LEPR Structurally contains two hemopoietin receptor domains, a fibronectin type III domain and a WSZWS domain within the extracellular region.
purity :
Highly Purified. ~98% (SDS-PAGE, HPLC)
form :
Supplied as a lyophilized powder from PBS, pH 7.4
storage stability :
Lyophilized powder may be stored at -70 degree C. Stable for 12 months at -20 degree C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
other info1 :
Biological Activity: Evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio.
other info2 :
Molecular Mass: The recombinant human LEPR consists of 829aa and has a predicted molecular mass of 95kD. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhLEPR is ~130 to 140 kD due to glycosylation.
products categories :
Molecular Biology; MB-Obesity
products description :
Leptin receptor (LEPR), also known as OB-R and B219, is a single transmembrane-domain receptor of the cytokine receptor family. Leptin receptor exists as homodimer and binds Leptin with high affinity, thus mediates the biological function of the adipocyte-specific hormone.
ncbi gi num :
82569700
ncbi acc num :
ABB83472.1
ncbi mol weight :
~95kD
size1 :
0.01 mg
price1 :
410 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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