protein

Herpes Simplex Virus II, Glycoprotein G, aa343-649, Recombinant (HSV II)

MBS635881

0.01 mg

505 USD

Recombinant Protein

Herpes Simplex Virus II, Glycoprotein G, aa343-649, Recombinant (HSV II)

[Herpes Simplex Virus II, Glycoprotein G, aa343-649]

[Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; heparan sulfate glucosamine 3-O-sulfotransferase 3A1; 3-OST-3A; h3-OST-3A; heparan sulfate 3-O-sulfotransferase 3A1; heparin-glucosamine 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1]

[HS3ST3A1; HS3ST3A1; 30ST3A1; 3OST3A1; 3OST3A1; HS3ST3A; 3-OST-3A; Heparan sulfate 3-O-sulfotransferase 3A1; h3-OST-3A]

HS3SA_HUMAN

>90%

Supplied as a liquid in PBS, 0.1% SDS, 1mM EDTA, pH 7.4

0.5mg/ml

Aliquot to avoid repeated freezing and thawing and store at -70 degree C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Shipping : Ships with dry ice

Source: Yeast

Molecular Biology; MB-Infectious Disease

Recombinant protein corresponding to Leu 343 to Asp 649 of Herpes Simplex Virus II, Glycoprotein G human superoxide dismutase (SOD) expressed in yeast cells.

61214551

Q9Y663.1

Q9Y663

~51kD

Disease Pathway (530764); Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway (82984); Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway (358); Glycosaminoglycan Metabolism Pathway (645297); HS-GAG Biosynthesis Pathway (645306); Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway (645304); MPS I - Hurler Syndrome Pathway (685537); MPS II - Hunter Syndrome Pathway (685538); MPS IIIA - Sanfilippo Syndrome A Pathway (685539); MPS IIIB - Sanfilippo Syndrome B Pathway (685540)

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Jul 2008]

HS3ST3A1: Sulfotransferase that utilizes 3 -phospho-5 -adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate. Belongs to the sulfotransferase 1 family. Protein type: Membrane protein, integral; Glycan Metabolism - heparan sulfate biosynthesis; Glycan Metabolism - glycosaminoglycan degradation; EC 2.8.2.23; Transferase. Chromosomal Location of Human Ortholog: 17p12. Cellular Component: Golgi membrane; integral to membrane. Molecular Function: sulfotransferase activity; [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity. Biological Process: glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis

0.01 mg

505 USD

0.05 mg

1305