product summary
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company name :
MyBioSource
product type :
protein
product name :
Actin, Cardiac
catalog :
MBS635219
quantity :
0.1 mg
price :
535 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS635219
products type :
Protein
products full name :
Actin, Cardiac
products short name :
Actin, Cardiac
other names :
actin, alpha cardiac muscle 1 proprotein; Actin, alpha cardiac muscle 1; actin, alpha cardiac muscle 1; actin, alpha, cardiac muscle 1; Alpha-cardiac actin
other gene names :
ACTC1; ACTC1; ACTC; ASD5; CMD1R; CMH11; LVNC4; ACTC
uniprot entry name :
ACTC_HUMAN
host :
Bovine heart
purity :
>98% (SDS-PAGE)
form :
Supplied as a lyophilized powder from 10mM Tris-acetate buffer, pH 8.0, 0.2mM CaCl2, 0.2mM ATP, 1mM DTT, 0.5% SDS.
concentration :
~1mg/ml (after reconstitution)
storage stability :
Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile H2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
tested application :
Gel Shift Assay (GS/EMSA)
app notes :
Suitable for use as a Protein standard in 1D and 2D SDS gel electrophoresis, in Immunoassays and for Immunization.
other info1 :
Isoelectric Point: pI 5.4. Reconstitution: Reconstitute to <1mg/ml with sterile ddH2O.
products categories :
Molecular Biology; MB-Actin Related Proteins
ncbi gi num :
4885049
ncbi acc num :
NP_005150.1
ncbi gb acc num :
NM_005159.4
uniprot acc num :
P68032
ncbi mol weight :
43kD
ncbi pathways :
Cardiac Progenitor Differentiation Pathway (712094); Cardiac Muscle Contraction Pathway (93344); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114229); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Myometrial Relaxation And Contraction Pathways (198759); Striated Muscle Contraction Pathway (198903)
ncbi summary :
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
uniprot summary :
ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Protein type: Contractile; Cytoskeletal; Motility/polarity/chemotaxis; Cell development/differentiation; Myosin-binding. Chromosomal Location of Human Ortholog: 15q14. Cellular Component: I band; extracellular space; sarcomere; focal adhesion; membrane; cytoplasm; actin filament; cytosol. Molecular Function: myosin binding; ATPase activity; ATP binding. Biological Process: response to drug; apoptosis; metabolic process; muscle thin filament assembly; actin filament-based movement; actomyosin structure organization and biogenesis; cardiac myofibril assembly; muscle filament sliding; response to ethanol; heart contraction; cardiac muscle morphogensis; actin-myosin filament sliding; negative regulation of apoptosis; cardiac muscle contraction. Disease: Atrial Septal Defect 5; Cardiomyopathy, Familial Hypertrophic, 11; Cardiomyopathy, Dilated, 1r
size1 :
0.1 mg
price1 :
535 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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