product summary
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company name :
MyBioSource
product type :
protein
product name :
Integrin alphaV, beta5
catalog :
MBS634845
quantity :
0.05 mg
price :
765 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS634845
products type :
Protein
products full name :
Integrin alphaV, beta5
products short name :
Integrin alphaV, beta5
other names :
integrin beta-5; Integrin beta-5; integrin beta-5; integrin, beta 5
other gene names :
ITGB5; ITGB5
uniprot entry name :
ITB5_HUMAN
host :
Human placenta
purity :
Affinity Purified. Purity verified by SDS-PAGE silver stain, under non-reducing conditions (95%). Two bands were detected corresponding to alpha V (145 kD) and beta5 (90 kD).
form :
Supplied as a liquid in 20mM Tris-HCL, pH 7.5, 150mM Sodium Chloride, 2 mM MgCl2, 0.2% Triton X-100. No preservative added.
concentration :
~0.2mg/ml
storage stability :
Aliquot to avoid repeated freezing and thawing and store at -70 degree C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Western Blot (WB)
app notes :
Suitable for use in Electrophoresis, Immunoblot (non-reducing) and Ligand Binding studies.
other info2 :
Recommended Dilutions: Optimal dilutions to be determined by the researcher.
products categories :
Molecular Biology; MB-Integrins
products description :
Integrin alphaV beta5 was purified from human placenta by affinity chromatography using immobilized monoclonal antibodies to alphaV beta5 integrin.
ncbi gi num :
20127446
ncbi acc num :
NP_002204.2
ncbi gb acc num :
NM_002213.3
uniprot acc num :
P18084
ncbi mol weight :
88,054 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway (477123); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); ECM Proteoglycans Pathway (833812)
uniprot summary :
ITGB5: Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V. Interacts with MYO10. Belongs to the integrin beta chain family. Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3q21.2. Cellular Component: focal adhesion; cell surface; leading edge; plasma membrane; phagocytic vesicle; receptor complex. Molecular Function: integrin binding; protein binding; receptor activity. Biological Process: integrin-mediated signaling pathway; antigen processing and presentation of peptide antigen via MHC class I; extracellular matrix organization and biogenesis; muscle contraction; cell-matrix adhesion; transforming growth factor beta receptor signaling pathway; stress fiber formation; antigen processing and presentation of exogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
size1 :
0.05 mg
price1 :
765 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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