product summary
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company name :
MyBioSource
product type :
protein
product name :
Factor Xa, BEGR (Biotin-EGR), Human
catalog :
MBS634686
quantity :
0.1 mg
price :
315 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS634686
products type :
Protein
products full name :
Factor Xa, BEGR (Biotin-EGR), Human
products short name :
Factor Xa, BEGR
host :
Human Plasma
purity :
Highly Purified. >95% (SDS-PAGE)
form :
Supplied as a liquid 20mM Hepes, pH 7.4, 150mM sodium chloride.
concentration :
2.3mg/ml
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
other info1 :
Specific Activity: ~1000u/mg. Extinction Coefficient: E1%1cm, 280nm= 11.6 (6). Mode of Action: Enzyme component of the prothrombinase complex. Structure: Two subunits, Mr=16,200 and 29,000 (6), NH2-terminal gla domain, two EGF domains. Percent Carbohydrate: 3.0% (8). Post-translational Modifications: Eleven gla residues, one beta-hydroxyaspartate
other info2 :
Localization: Plasma
products categories :
Molecular Biology; MB-Coagulation Factors
products description :
Activation of the zymogen, factor X, by either the intrinsic or extrinsic factor Xase complexes produces the active serine protease factor Xa (1,2). The activation of factor X requires proteolytic cleavage of the heavy chain, resulting in the release of an activation glycopeptide. The heavy chain region in factor Xa contains the serine protease catalytic domain, while the light chain, as in the zymogen, contains the membrane binding domain. Factor Xa participates in the prothrombinase complex, which catalyzes the rapid conversion of prothrombin to thrombin. Protothrombinase is an enzyme complex composed of factor Xa (enzyme) and factor Va (cofactor) assembled on a cellular suface in the presence of calcium ions. Although factor Xa can independently catalyze the activation o prothrombin, the rate at which this reaction occurs is increased nearly 300,000-fold with complete assembly of the prothrombinase complex. The clotting activity of factor Xa in vivo is terminated by wither inactivation of the cofactor, factor Va, or by direct inhibition of factor Xa by inhibitors, such as ATIII, after disassembly of the prothrombinase complex.
ncbi mol weight :
46,000
size1 :
0.1 mg
price1 :
315 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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