protein

Insulin-Like Growth Factor Binding Protein 3 (IGFBP3, tcag7.703, BP-53, IBP3, IGF-binding protein 3, Growth hormone-dependent binding protein) (Control Peptide)

MBS634420

0.1 mg

350 USD

Protein

Insulin-Like Growth Factor Binding Protein 3 (IGFBP3, tcag7.703, BP-53, IBP3, IGF-binding protein 3, Growth hormone-dependent binding protein) (Control Peptide)

Insulin-Like Growth Factor Binding Protein 3

insulin-like growth factor-binding protein 3; Insulin-like growth factor-binding protein 3; insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; insulin-like growth factor binding protein-3; insulin-like growth factor binding protein 3

IGFBP3; IGFBP3; IGFBP-3; IBP-3; IGF-binding protein 3; IGFBP-3

IBP3_BOVIN

C-RYKVDYESQSTDTQN

Recognizes human IGFBP3. Species Crossreactivity: mouse, rat, canine.

Highly Purified

Supplied as a lyophilized powder in PBS.

~0.5mg/ml (after reconstitution)

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

ELISA (EL/EIA). Other applications not tested.

Suitable for use in ELISA. Optimal dilutions to be determined by the researcher.

Control No.: C14121260. Reconstitution: Reconstitute with 200ul sterile ddH2O.

Growth Factors, Cytokines; Growth Factors-IGF

C-terminus, aa RYKVDYESQSTDTQN.

27807007

NP_776981.1

NM_174556.1

P20959

31,570 Da

Metabolism Of Proteins Pathway (827137); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (827203); Transcriptional Misregulation In Cancer Pathway (522997); Transcriptional Misregulation In Cancer Pathway (522987); P53 Signaling Pathway (84294); P53 Signaling Pathway (465)

Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Subunit structure: Interacts with HN. Interacts with TMEM219 . By similarity. Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with XLKD1. Ref.6. Subcellular location: Secreted. Tissue specificity: Plasma; expressed by most tissues. Post-translational modification: Phosphorylation sites are present in the extracellular medium . By similarity. Sequence similarities: Contains 1 IGFBP N-terminal domain.Contains 1 thyroglobulin type-1 domain.

0.1 mg

350 USD