catalog number :
MBS633567
products full name :
Lactoferricin B (Lactoferricin-B, Lfcin-B)
products short name :
Lactoferricin B
products name syn :
Anti -Lactoferricin B (Lactoferricin-B, Lfcin-B)
other names :
lactoferricin b 15
specificity :
Recognizes bovine Lactoferricin B. Is not present in lactoferrin in human, pig, mouse, goat, rabbit, horse, rat, cockroach and African clawed frog.
purity :
Purified. Purified
form :
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
Suitable for use in Western Blot and ELISA, as detection in immunoassay. Dilution: Western Blot: 1:10, ELISA: detection
other info1 :
Immunogen: Lactoferricin B is highly specific for bovine Lactoferricin B.
products categories :
Antibodies; Abs to Serum Proteins
products description :
Bovine Lactoferricin B is highly specific for bovine Lactoferricin B. This peptide is derived by enzymatic cleavage of lactoferrin which is a member of the transferring family of metal-binding proteins found in milk and other secretory fluids and also in blood. Cleavage by pepsin of bovine lactoferrin leads to the release of Lactoferrincin B (aa17-41). This peptide is highly basic, possessing five Arg (R) and three Lys (K) residues. In addition, a number of Trp (W) and the Phe (F) aromatic residues are present. The two Cys (C) residues from lactoferricin B form a disulfide bond, generating an almost completely cyclical peptide. Nevertheless, the disulfide bond is not required for the antimicrobial potency. Several studies have shown that Lactoferricin B has a broad-spectrum activity against various Gram-positive and Gram-negative bacteria. In addition the peptide has been shown to have antifungal, antiviral and antitumour activity and to bind lipolysaccharides (LPS, endotoxin). Moreover, it is known to stimulate the adaptive immune response and has anti-inflammatory properties. Lactoferricin B belongs to a large group of cationic antimicrobial peptides.
ncbi acc num :
ABB58824.1