antibody

Chorionic Gonadotropin, Human, beta (hCGb)

MBS632805

1 mg

515 USD

monoclonal

mouse

nonconjugated

[8.F.52B]

Antibody

Chorionic Gonadotropin, Human, beta (hCGb)

[Chorionic Gonadotropin, beta]

[Anti -Chorionic Gonadotropin, Human, beta (hCGb)]

[chorionic gonadotropin, beta polypeptide 8; chorionic gonadotropin, beta polypeptide 8; chorionic gonadotropin beta 8 subunit; chorionic gonadotropin, beta polypeptide 8]

[CGB8]

Monoclonal

IgG1

[8.F.52B]

Mouse

Recognizes human Chorionic Gonadotropin, beta. Contaminants: hCG: <90%; hTSH,hLH,hFSH:<=1%

Purified by chromatography

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

8.7 mg/mL

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Suitable for use in very sensitive and specific gold or latex based single step assay.Other applications not tested.

Optimal dilutions to be determined by the researcher. Recommended Pair: Suitable use as the detection or conjugate (label) antibody. Matched to MBS631882 as the capture or solid phase anitbody.

Immunogen: Highly purified Human Chrorionic Gonadotropin,ß. Grade: Highly purified. Affinity Constant: ~8.0x10e9L/mole.

Antibodies; Abs to Hormones, Steroids

Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.

15426252

NP_000728.1

NM_033183.2

Glycoprotein Hormones Pathway (160989); Metabolism Of Proteins Pathway (106230); Peptide Hormone Biosynthesis Pathway (160988); Peptide Hormone Metabolism Pathway (771603)

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

1 mg

515 USD