catalog number :
MBS632257
products full name :
MRP7 (Multidrug Resistance-associated Protein 7, ATP-binding Cassette Sub-family C Member 10, ABCC10, EST182763, SIMRP7)
products short name :
MRP7
products name syn :
Anti -MRP7 (Multidrug Resistance-associated Protein 7, ATP-binding Cassette Sub-family C Member 10, ABCC10, EST182763, SIMRP7)
other names :
multidrug resistance-associated protein 7 isoform MRP7; Multidrug resistance-associated protein 7; multidrug resistance-associated protein 7; OTTHUMP00000016438; OTTHUMP00000016441; ATP-binding cassette sub-family C member 10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; ATP-binding cassette sub-family C member 10
other gene names :
ABCC10; ABCC10; MRP7; SIMRP7; EST182763; MRP7; SIMRP7
uniprot entry name :
MRP7_HUMAN
specificity :
Recognizes an internal epitope of human MRP7 (ABCC10) at ~160kD.
purity :
Supernatant. Supernatant
form :
Supplied as a liquid in 0.7% BSA, 0.1% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
app notes :
Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Dilution: Western Blot: 1:20-1:50. Immunohistochemistry (Acetone fixed frozen): 1:20. Immunocytochemistry (Acetone fixed): 1:20-1:50
other info1 :
Immunogen: Bacterial fusion protein of human MRP7, aa194-272.
products categories :
Antibodies; Abs to Multi Drug Resistance (MDR)
ncbi acc num :
NP_001185863.1
ncbi gb acc num :
NM_001198934.1
ncbi mol weight :
161,629 Da
ncbi pathways :
ABC Transporters Pathway (83035); ABC Transporters Pathway (436)
ncbi summary :
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
uniprot summary :
ABCC10: ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family; Transporter. Chromosomal Location of Human Ortholog: 6p21.1. Cellular Component: lysosomal membrane; plasma membrane; integral to membrane. Molecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP binding. Biological Process: metabolic process; transmembrane transport