antibody

Chorionic Gonadotropin, Human, beta (hCGb) (Gold)

MBS631600

10 mL

745 USD

monoclonal

mouse

gold

[9.F.55]

ELISA, enzyme immunoassay

Antibody

Chorionic Gonadotropin, Human, beta (hCGb) (Gold)

[Chorionic Gonadotropin, beta]

[Anti -Chorionic Gonadotropin, Human, beta (hCGb) (Gold)]

[chorionic gonadotropin, beta polypeptide 8; chorionic gonadotropin, beta polypeptide 8; chorionic gonadotropin beta 8 subunit; chorionic gonadotropin, beta polypeptide 8]

[CGB8]

Monoclonal

IgG1

[9.F.55]

Mouse

Human

Recognizes hCG beta and HCG. Does not crossreact with LH, FSH and TSH.

Affinity Purified. Purified by immunoaffinity chromatography prior to labeling.

Supplied as a liquid suspension in PBS, pH7.4, BSA, 0.09% sodium azide. Labeled with 40nm colloidial gold particle OD540nm = 10.

May be stored at 4 degree C. For long-term storage, aliquot and store at 4 degree C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Gold conjugates are light sensitive.

ELISA (EL/EIA)

Suitable for use in ELISA. Suitable for use in very sensitive and specific gold or latex based single step assay. Other applications have not been tested. Optimal dilutions to be determined by researcher.

Type: Mab. Immunogen: Purified human Chorionic Gonadotropin, beta.

Antibodies; Abs to Hormones, Steroids

Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera, but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a- and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG, but negative for EMA and AFP, is probably a choriocarcinoma.

15426252

NP_000728.1

NM_033183.2

Glycoprotein Hormones Pathway (160989); Metabolism Of Proteins Pathway (106230); Peptide Hormone Biosynthesis Pathway (160988); Peptide Hormone Metabolism Pathway (771603)

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

10 mL

745 USD