FSHB, ID (T70) (Follitropin Subunit beta, Follicle-stimulating Hormone beta Subunit, FSH-beta, FSH-B, Follitropin beta Chain) | MyBioSource MBS630283 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FSHB, ID (T70) (Follitropin Subunit beta, Follicle-stimulating Hormone beta Subunit, FSH-beta, FSH-B, Follitropin beta Chain)

catalog :

MBS630283

quantity :

0.2 mL

price :

500 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS630283

products type :

Antibody

products full name :

FSHB, ID (T70) (Follitropin Subunit beta, Follicle-stimulating Hormone beta Subunit, FSH-beta, FSH-B, Follitropin beta Chain)

products short name :

FSHB

products name syn :

Anti -FSHB, ID (T70) (Follitropin Subunit beta, Follicle-stimulating Hormone beta Subunit, FSH-beta, FSH-B, Follitropin beta Chain)

other names :

follitropin subunit beta; Follitropin subunit beta; follitropin subunit beta; FSH-B; FSH-beta; follitropin beta chain; follitropin, beta chain; follicle-stimulating hormone beta subunit; follicle stimulating hormone, beta polypeptide; Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain

other gene names :

FSHB; FSHB; FSH-B; FSH-beta

uniprot entry name :

FSHB_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

specificity :

Recognizes human FSHB.

purity :

Purified. Purified by ammonium sulfate precipitation.

form :

Supplied as a liquid in PBS, 0.09% sodium azide.

storage stability :

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

tested application :

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1000. Western Blot: 1:50-1:100. Immunohistochemistry: 1:50-1:100

other info1 :

Immunogen: Synthetic peptide corresponding to an region between aa62-91 near the Center (T70) region of human FSHB, conjugated to KLH.

products categories :

Antibodies; Abs to Hormones, Steroids

products description :

FSHB stimulates development of follicle and spermatogenesis in the reproductive organs.

ncbi gi num :

66528995

ncbi acc num :

NP_001018090.1

ncbi gb acc num :

NM_001018080.1

uniprot acc num :

P01225

ncbi mol weight :

14,700 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); FSH Signaling Pathway (672455); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Glycoprotein Hormones Pathway (160989); GnRH Signaling Pathway (83091); GnRH Signaling Pathway (502); Hormone Ligand-binding Receptors Pathway (106369); Metabolism Of Proteins Pathway (106230)

ncbi summary :

The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

uniprot summary :

FSHB: Stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle- stimulating hormone deficiency (IFSHD). Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Belongs to the glycoprotein hormones subunit beta family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11p13. Cellular Component: cytoplasm; extracellular region. Molecular Function: follicle-stimulating hormone activity; protein binding; hormone activity. Biological Process: progesterone biosynthetic process; follicle-stimulating hormone signaling pathway; peptide hormone processing; female gamete generation; Sertoli cell proliferation; female pregnancy; signal transduction; cellular protein metabolic process; regulation of osteoclast differentiation; transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; positive regulation of bone resorption; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell migration. Disease: Follicle-stimulating Hormone Deficiency, Isolated

size1 :

0.2 mL

price1 :

500 USD

more info or order :

MyBioSource product webpage