product summary
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company name :
MyBioSource
product type :
antibody
product name :
KIR2DL5B (Killer Cell Immunoglobulin-like Receptor 2DL5B, KIR2DL5, KIR2DL5.2, CD158 Antigen-like Family Member F2, CD158F2, CD158F, Killer Cell Immunoglobulin-like Receptor 2DLX, KIR2DLX)
catalog :
MBS629460
quantity :
0.2 mL
price :
500 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry, FACS, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS629460
products type :
Antibody
products full name :
KIR2DL5B (Killer Cell Immunoglobulin-like Receptor 2DL5B, KIR2DL5, KIR2DL5.2, CD158 Antigen-like Family Member F2, CD158F2, CD158F, Killer Cell Immunoglobulin-like Receptor 2DLX, KIR2DLX)
products short name :
KIR2DL5B
products name syn :
Anti -KIR2DL5B (Killer Cell Immunoglobulin-like Receptor 2DL5B, KIR2DL5, KIR2DL5.2, CD158 Antigen-like Family Member F2, CD158F2, CD158F, Killer Cell Immunoglobulin-like Receptor 2DLX, KIR2DLX)
other names :
killer cell immunoglobulin-like receptor 2DL5B; Killer cell immunoglobulin-like receptor 2DL5B; killer cell immunoglobulin-like receptor 2DL5B; killer cell Ig-like receptor; CD158 antigen-like family member F2; killer cell immunoglobulin-like receptor 2DLX; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B; CD158 antigen-like family member F2; Killer cell immunoglobulin-like receptor 2DLX
other gene names :
KIR2DL5B; KIR2DL5B; KIR2DL5; KIR2DLX; KIR2DL5.2; CD158F; CD158F2; KIR2DL5; KIR2DLX
uniprot entry name :
KI2LB_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
specificity :
Recognizes human KIR2DL5B.
purity :
Affinity Purified. Purified by Protein A and peptide affinity chromatography.
form :
Supplied as a liquid in PBS, 0.09% sodium azide.
storage stability :
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
tested application :
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
app notes :
Suitable for use in ELISA, Immunohistochemistry, Flow Cytometry and Western Blot. Dilution: ELISA: 1:1000. Western Blot: 1:100-1:500. Immunohistochemistry: 1:50-1:100. Flow cytometry: 1:10-1:50
other info1 :
Immunogen: Synthetic peptide corresponding to the center region, between aa270-299, of human KIR2DL5B, conjugated to KLH.
products categories :
Antibodies; Abs to Receptors
products description :
KIR2DL5B is a receptor on natural killer (NK) cells for HLA-C alleles. It inhibits the activity of NK cells thus preventing cell lysis.
ncbi gi num :
66267727
ncbi acc num :
NP_001018091.1
ncbi gb acc num :
NM_001018081.1
uniprot acc num :
Q8NHK3
ncbi mol weight :
40,607 Da
ncbi summary :
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq]
uniprot summary :
KIR2DL5B: Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis. Belongs to the immunoglobulin superfamily. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: integral to membrane; plasma membrane
size1 :
0.2 mL
price1 :
500 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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